Electrocardiographic differentiation between 'benign T-wave inversion' and arrhythmogenic right ventricular cardiomyopathy

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Gherardo FinocchiaroSanjay Sharma

Abstract

To characterize the most common electrocardiographic (ECG) abnormalities in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC), including anterior T-wave inversion (TWI) and to compare the characteristics of TWI in patients with ARVC and in a cohort of young healthy athletes and sedentary individuals. The study population consisted of 162 patients with a definite diagnosis of ARVC and 129 young controls with anterior TWI. Cardiac disease was excluded in all controls after a comprehensive diagnostic work-up. The ECG was abnormal in 131 patients with ARVC (81%). Abnormalities included anterior TWI (n = 82, 51%), QRS duration ratio V2:V5 >1.2 (n = 51, 31%), prolonged terminal S wave activation duration in V2 >55 ms (n = 42, 26%), inferior TWI (n = 30, 18%), and lateral TWI (n = 26, 16%). The J-point preceding anterior TWI was <0.1 mV in 80/82 (98%) patients with ARVC and in 98 (76%) controls. Among the ARVC patients with anterior TWI, 62 (77%) showed at least one additional abnormal feature, most commonly QRS duration ratio V2:V5 > 1.2 (52%) and inferior or lateral TWI (47%). The ECG is frequently abnormal in patients with ARVC and anterior TWI is the most common feature. Anterior TWI is usually accompanied by ot...Continue Reading

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Jan 7, 2017·Journal of the American College of Cardiology·Aneil MalhotraSanjay Sharma
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Citations

Apr 4, 2020·European Journal of Heart Failure·Gherardo FinocchiaroGianfranco Sinagra
Jul 1, 2020·Pacing and Clinical Electrophysiology : PACE·Alessandro ZorziDomenico Corrado
Apr 18, 2020·Journal of Cardiovascular Translational Research·Alessandro ZorziDomenico Corrado
Apr 17, 2020·European Journal of Preventive Cardiology·François Carré, Frédéric Schnell
Dec 23, 2019·Current Treatment Options in Cardiovascular Medicine·Mark Abela, Sanjay Sharma
Jul 16, 2021·Heart Failure Reviews·Nicoletta OrphanouAris Anastasakis
Sep 5, 2021·The International Journal of Cardiovascular Imaging·Gherardo FinocchiaroGerald Carr-White
Dec 12, 2021·European Heart Journal·Deepthi RajanJacob Tfelt-Hansen

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