Electrocardiographic findings and incident coronary heart disease among participants in the Atherosclerosis Risk in Communities (ARIC) study

The American Journal of Cardiology
Daniella B MachadoAaron R Folsom

Abstract

The associations of many electrocardiographic (ECG) abnormalities at rest with incident coronary heart disease (CHD) are not completely established, and whether individual ECG abnormalities convey similar risk across gender and race is uncertain. We studied the independent association of several ECG findings with incident CHD, testing for effect modification by gender and race, in a large, population-based, prospective cohort study. Findings from the baseline 12-lead electrocardiograms in 1987 to 1989 were classified according to the Minnesota Code in 12,987 black and white men and women, aged 45 to 64 years, who were initially free of CHD and the use of specific cardiac medications. The incidence of CHD was ascertained through 2000. After adjustment for multiple cardiovascular risk factors, the ECG findings that had the highest hazard rate ratios (HRRs) for incident CHD, when considered singly, were left ventricular hypertrophy with ST-T strain pattern in white men (HRR 6.50) and in black women (HRR 2.31) and, in the whole cohort, major (HRR 2.27) and minor (HRR 2.47) ST depression and major T-wave abnormalities (HRR 2.12). Statistically significant associations were also found in the whole cohort for minor Q waves and left ve...Continue Reading

References

Nov 21, 1996·The New England Journal of Medicine·R F Gillum
Mar 8, 2000·Current Problems in Cardiology·E A AshleyV F Froelicher
Dec 25, 2003·The American Journal of Medicine·John RobbinsJohn S Gottdiener

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Citations

Jul 30, 2014·Metabolic Syndrome and Related Disorders·Ebenezer Adekunle AjayiOlatayo Adekunle Adeoti
Aug 29, 2013·Journal of Electrocardiology·Karim Sallam, Victor Froelicher
Dec 3, 2014·Journal of Epidemiology and Global Health·Matthew B SellersElsayed Z Soliman
Oct 4, 2011·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Leonard Ilkhanoff, Bradley P Knight
Nov 26, 2015·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Fábio Jean Goulart SeboldDaisson José Trevisol
May 5, 2007·Annals of Epidemiology·Francois M BooyseEdlue M Tabengwa
Jan 17, 2012·The American Journal of Cardiology·Ronald J PrineasUNKNOWN Reasons for Geographic and Racial Differences in Stroke (REGARDS) Investigators
Jul 13, 2011·Annals of Medicine·M Juhani JunttilaRobert J Myerburg
Feb 23, 2013·Journal of the American College of Cardiology·Joseph A WalshDonald M Lloyd-Jones
Jul 17, 2012·International Journal of Cardiology·Karen SliwaSimon Stewart
Dec 23, 2009·Asian Cardiovascular & Thoracic Annals·Mahnoosh ForoughiSeyed-Ahmad Hassantash
Mar 7, 2013·Journal of Hypertension·Søren Zöga DiederichsenAxel Cosmus Pyndt Diederichsen
Dec 19, 2013·Revista de saúde pública·Antonio Luiz RibeiroSandhi Maria Barreto
Sep 13, 2020·BMC Cardiovascular Disorders·Liping YuUNKNOWN China National Diabetes and Metabolic Disorders Study Group
Feb 23, 2021·Frontiers in Physiology·Mira Anette E HaukilahtiHeikki V Huikuri

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