PMID: 8606273Mar 1, 1996Paper

Electrocardiographic measurement of infarct size after thrombolytic therapy

Journal of the American College of Cardiology
C P JuergensR W Jeremy

Abstract

We examined the utility of the 32-point QRS score from the 12-lead electrocardiogram (ECG) for measurement of the ischemic risk region and infarct size in patients receiving thrombolytic therapy. The QRS score offers a means of evaluating the therapeutic benefit of thrombolytic therapy by comparing final infarct size with the initial extent of ischemic myocardium. The study included 38 patients (34 men, 4 women; mean [+/-SD] age 54 +/- 10 years) with a first infarction (18 anterior, 20 inferior). The maximal potential QRS score (QRS0) was assigned to all leads with >/= 100-microV ST elevation on the initial ECG. The QRS scores were calculated at 7 and 30 days after infarction. Left ventricular ejection fraction was measured by radionuclide ventriculography at 1 month. Twenty-eight patients had thallium (Tl)-201 and technetium (Tc)-99m pyrophosphate tomographic measurement of the ischemic region and infarct size. The QRS0 was 10.3 +/- 3.1 (mean +/- SD) for anterior and 10.4 +/- 3.5 for inferior infarcts. The QRS scores were similar at 7 and 30 days for both anterior (5.6 +/- 3.4 vs. 5.5 +/- 3.4) and inferior infarcts (3.7 +/- 2.6 vs. 2.9 +/- 2.2). The day 7 QRS score and ejection fraction at 1 month were inversely correlated (r ...Continue Reading

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Citations

Dec 13, 2005·International Journal of Cardiology·Petr TousekChristian Firschke
Feb 15, 2003·The American Journal of Medicine·Costantina ManesScott D Solomon
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Jan 7, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Masami KosugeSatoshi Umemura
Feb 26, 2008·Circulation Journal : Official Journal of the Japanese Circulation Society·Jun OkudaKazuo Kimura
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Feb 9, 2007·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Jakub PrzyluskiUNKNOWN ANIN Myocardial Infarction Registry
Dec 15, 2005·Heart, Lung & Circulation·Yi ZhangRichmond W Jeremy
Apr 29, 2006·International Journal of Cardiology·Anne VorlatChristiaan J Vrints
Sep 23, 2014·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Minna M KylmäläLauri Toivonen
Apr 24, 2007·Journal of the American College of Cardiology·Trond VartdalThor Edvardsen
Jul 1, 2005·European Heart Journal·Stefano SavonittoChristopher B Granger
Jul 1, 2020·Terapevticheskiĭ arkhiv·E A ShigotarovaV E Oleynikov
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