Electrocardiographic patterns and long-term clinical outcome in cardiac resynchronization therapy

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Mads B KronborgPeter T Mortensen

Abstract

The present study aims to identify the predictive value of electrocardiographic (ECG) patterns on long-term clinical and echocardiographic outcome in patients treated with cardiac resynchronization therapy (CRT). Clinical information including a standard 12-lead ECG was collected from patient files in consecutive patients treated with CRT from 1997 to 2007. Symptomatic response was defined as improvement in New York Heart Association class (> or =1) and echocardiographic response as improvement in left ventricular ejection fraction of > or =5% absolute. We included 659 patients [median age 66 years, 526 (80%) male]. There was a higher all-cause and cardiac mortality in patients with left bundle branch block (LBBB), prolonged PR interval, right-axis deviation combined with LBBB in the pre-implant ECG, and no QRS reduction after CRT. Patients with right bundle branch block and patients with an intermediate QRS duration (150-200 ms) had a higher chance of symptomatic improvement, and patients with normal PR interval and normal axis in LBBB had a higher chance of echocardiographic improvement. Cardiac resynchronization therapy does not change the predictive value of ECG patterns in heart failure patients with bundle branch block, w...Continue Reading

References

Mar 22, 2001·The New England Journal of Medicine·S CazeauUNKNOWN Multisite Stimulation in Cardiomyopathies (MUSTIC) Study Investigators
Jun 14, 2002·The New England Journal of Medicine·William T AbrahamUNKNOWN MIRACLE Study Group. Multicenter InSync Randomized Clinical Evaluation
May 29, 2003·JAMA : the Journal of the American Medical Association·James B YoungUNKNOWN Multicenter InSync ICD Randomized Clinical Evaluation (MIRACLE ICD) Trial Investigators
Mar 11, 2004·Pacing and Clinical Electrophysiology : PACE·Sander G MolhoekMartin J Schalij
May 21, 2004·The New England Journal of Medicine·Michael R BristowUNKNOWN Comparison of Medical Therapy, Pacing, and Defibrillation in Heart Failure (COMPANION) Investigators
Aug 6, 2004·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Valérie Valls-BertaultJean-Jacques Blanc
Nov 18, 2004·Pacing and Clinical Electrophysiology : PACE·Matthew R ReynoldsUNKNOWN Miracle ICD Investigators
Dec 3, 2004·Journal of Cardiovascular Electrophysiology·Tamara HorwichLeslie Saxon
Mar 9, 2005·The New England Journal of Medicine·John G F ClelandUNKNOWN Cardiac Resynchronization-Heart Failure (CARE-HF) Study Investigators
Jun 1, 2005·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Cesar A EgoavilBehzad B Pavri
Dec 20, 2005·Journal of the American College of Cardiology·Amir Kashani, S Serge Barold
Mar 11, 2006·European Heart Journal·Nathaniel M HawkinsJohn J V McMurray
Mar 29, 2006·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Zayd A EldadahRonald D Berger
Apr 22, 2006·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Carl J HöijerJohan Brandt
Aug 23, 2006·Pacing and Clinical Electrophysiology : PACE·Ibrahim MaraiMichael Glikson
Mar 7, 2007·Pacing and Clinical Electrophysiology : PACE·Paul A Levine
Oct 9, 2007·Journal of the American College of Cardiology·Melissa J ByrneAlbert C Lardo
Jul 16, 2008·European Journal of Heart Failure·Mads Brix KronborgJens Cosedis Nielsen
Jan 6, 2009·The American Journal of Cardiology·Evan C Adelstein, Samir Saba
Mar 25, 2009·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Paul W X FoleyFrancisco Leyva
Jun 10, 2009·European Journal of Heart Failure·Renaud GervaisUNKNOWN CARE-HF investigators
Aug 8, 2009·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Mads Brix KronborgPeter Thomas Mortensen

❮ Previous
Next ❯

Citations

Mar 14, 2012·Herzschrittmachertherapie & Elektrophysiologie·A-M Sinha
Jun 7, 2011·European Heart Journal·Jonathan BuberIlan Goldenberg
Apr 21, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·S Serge Barold, Bengt Herweg
May 15, 2012·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Thanh-Thuy Vo ThangFrançois Harel
Jun 16, 2012·Heart Rhythm : the Official Journal of the Heart Rhythm Society·J Claude DaubertChristophe Leclercq
Nov 15, 2011·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Julia KöbeLars Eckardt
May 30, 2013·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Fredrik Holmqvist, James P Daubert
Dec 23, 2011·Pacing and Clinical Electrophysiology : PACE·S Serge Barold, Bengt Herweg
May 7, 2013·The American Journal of Cardiology·Parin J Patel, Ralph J Verdino
Jun 13, 2015·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Łukasz JanuszkiewiczKimberly A Parks
Apr 30, 2015·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Nikhil P JoshiBehzad B Pavri
Mar 21, 2015·Journal of Women's Health·Naomi D HerzDaniel A Caños
Dec 8, 2015·Journal of Cardiovascular Electrophysiology·Laura PerrottaLuigi Padeletti
Apr 5, 2018·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Javier García-SearaJosé Ramón González Juanatey
Sep 17, 2017·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Theodora NikolaidouAndrew L Clark
May 29, 2018·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Marek JastrzębskiDanuta Czarnecka
May 23, 2014·Expert Review of Cardiovascular Therapy·Giuseppe StabileAntonio De Simone
Nov 8, 2018·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Marek JastrzebskiDanuta Czarnecka
Apr 1, 2016·JACC. Clinical Electrophysiology·Theodora NikolaidouAndrew L Clark
Jun 8, 2021·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Kamil SedláčekDan Wichterle
Aug 3, 2021·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Marek JastrzębskiPugazhendhi Vijayaraman
Feb 11, 2011·Current Opinion in Cardiology

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.