PMID: 15228108Jul 2, 2004Paper

Electrochemical determination of serotonin and the competitive adsorption with dopamine at 5,5-ditetradecyl-2-(2-trimethylammonioethyl)-1,3-dioxane bromide lipid film modified by glassy carbon electrode

Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry
Jing-Ming Gong, X Lin

Abstract

A novel and effective approach to sensitively determine serotonin, known as 5-hydroxytryptamine (5-HT), has been proposed based on a 5,5-ditetradecyl-2-(2-trimethylammonioethyl)-1,3-dioxane bromide (DTDB) self-assembled lipid bilayer membrane modified glassy carbon electrode (DTDB/GCE). A DTDB/GCE shows the strong electrocatalysis for the oxidation of 5-HT, with the peak potential shifted to less positive value of 0.376 V vs. SCE, and effectively eliminates the interference from ascorbic acid (AA), even in the presence of 100-fold concentration of AA. Differential pulse voltammetry (DPV) gave a linear current for 5-HT from 2.0 x 10(-7) to 1.0 x 10(-5) M. At the DTDB/GCE, the oxidation of 5-HT was controlled by the adsorption process; for 5-HT coexisting with DA, the competitive adsorption was observed.

References

Dec 15, 1987·Analytical Chemistry·M SugawaraY Umezawa
May 3, 2001·Journal of Photochemistry and Photobiology. B, Biology·H GaoH T Tien
May 16, 2002·Bioelectrochemistry·Agnieszka ZebrowskaZenon Łotowski
Nov 9, 2002·Toxicology in Vitro : an International Journal Published in Association with BIBRA·N HadiJ Iqbal
Apr 18, 2003·Bioelectrochemistry·Jian-Shan YeFwu-Shan Sheu

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Citations

Jan 17, 2020·Sensors·Sylwia BalutaJoanna Cabaj
Dec 8, 2020·ACS Chemical Neuroscience·Sasya MadhurantakamUma Maheswari Krishnan

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