Electrochemical radical reactions of alkyl iodides: a highly efficient, clean, green alternative to tin reagents.

Chemical Science
Diyuan LiJonathan D Wilden

Abstract

An electrochemical 'redox-relay' system has been developed which allows the generation of C-centered radicals. Intermolecular 'tin-like' radical reactions can subsequently be conducted under the most benign of conditions. The yields and efficiency of the processes are competitive and even superior in most cases to comparable conditions with tributyltin hydride. The use of air and electricity as the promotor (instead of a tin or other reagent) combined with the aqueous reaction media make this a clean and 'green' alternative to these classic C-C bond forming processes.

References

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Dec 5, 2018·Nature Chemistry·Bertrand Schweitzer-ChaputPaolo Melchiorre

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Citations

May 29, 2021·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Diego Francisco Chicas-Baños, Bernardo A Frontana-Uribe
Aug 3, 2021·Chemical Communications : Chem Comm·Tsz-Kan MaJonathan D Wilden

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