Electrochemiluminescence detection in microfluidic cloth-based analytical devices

Biosensors & Bioelectronics
Wenrong GuanChunsun Zhang

Abstract

This work describes the first approach at combining microfluidic cloth-based analytical devices (μCADs) with electrochemiluminescence (ECL) detection. Wax screen-printing is employed to make cloth-based microfluidic chambers which are patterned with carbon screen-printed electrodes (SPEs) to create truly disposable, simple, inexpensive sensors which can be read with a low-cost, portable charge coupled device (CCD) imaging sensing system. And, the two most commonly used ECL systems of tris(2,2'-bipyridyl)ruthenium(II)/tri-n-propylamine (Ru(bpy)3(2+)/TPA) and 3-aminophthalhydrazide/hydrogen peroxide (luminol/H2O2) are applied to demonstrate the quantitative ability of the ECL μCADs. In this study, the proposed devices have successfully fulfilled the determination of TPA with a linear range from 2.5 to 2500μM with a detection limit of 1.265μM. In addition, the detection of H2O2 can be performed in the linear range of 0.05-2.0mM, with a detection limit of 0.027mM. It has been shown that the ECL emission on the wax-patterned cloth device has an acceptable sensitivity, stability and reproducibility. Finally, the applicability of cloth-based ECL is demonstrated for determination of glucose in phosphate buffer solution (PBS) and artifi...Continue Reading

References

Jul 8, 2011·Lab on a Chip·Paridhi BhandariDhananjaya Dendukuri
Sep 29, 2011·ACS Applied Materials & Interfaces·Tracie L OwensVictor Breedveld
Nov 18, 2011·Lab on a Chip·Azadeh NilghazMohammed Rafiq Abdul Kadir
Aug 10, 2012·ACS Applied Materials & Interfaces·Fehime VatanseverIgor Luzinov
Oct 16, 2012·Analytica Chimica Acta·Sandeep Kumar Vashist
May 9, 2013·Lab on a Chip·Ali Kemal YetisenChristopher R Lowe
Apr 30, 2014·The Analyst·Radha S P MalonEmma P Córcoles

❮ Previous
Next ❯

Citations

Oct 31, 2015·Biosensors & Bioelectronics·Mohtashim H ShamsiAaron R Wheeler
May 16, 2017·Chemistry, an Asian Journal·Chien-Wei HsuLuisa De Cola
Mar 30, 2016·Lab on a Chip·Mokhamad Fakhrul UlumDedy Hermawan Bagus Wicaksono
Mar 7, 2021·Micromachines·Mikail TemirelSavas Tasoglu
Jan 30, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Souvick ChatterjeeConstantine M Megaridis
Jan 15, 2019·ACS Combinatorial Science·Syamak FarajikhahGordon Wallace
Oct 15, 2021·Analytical Methods : Advancing Methods and Applications·Deonir AgustiniDosil Pereira de Jesus

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.