PMID: 9193732May 1, 1997Paper

Electrocochleographic analysis of the suppression of tinnitus by electrical promontory stimulation

Audiology : Official Organ of the International Society of Audiology
K WatanabeT Yagi

Abstract

To investigate the origin, and evaluate the mechanism by which tinnitus is suppressed we performed electrical promontory stimulation (EPS) in 56 patients with tinnitus, and measured the compound action potential (CAP) using electrocochleography before and after EPS. In the group of patients in whom tinnitus was suppressed, the CAP amplitudes increased significantly, whereas the latencies showed no remarkable change. In the group of patients in whom tinnitus was not suppressed, both the CAP amplitudes and latencies exhibited no significant change. These data indicate that the effect on the cochlear nerve plays an important role in the suppression of tinnitus by EPS. The CAP reflects the number of the auditory nerve fibers which discharge synchronously. It is speculated that an increase of the CAP amplitudes is caused by synchronizing discharges of the auditory nerve fibers, and that the mechanism by which EPS suppresses tinnitus may be related to synchronizing these discharges.

Associated Clinical Trials

Nov 30, 2018·Matthew L. Carlson, M.D.

References

May 1, 1977·British Journal of Audiology·J M Graham, J W Hazell
Jul 1, 1973·The Annals of Otology, Rhinology, and Laryngology·M M MerzenichM Reid
Aug 1, 1995·Nihon Jibiinkoka Gakkai kaiho·D Ohkawara, K Watanabe
Jan 1, 1964·Acta Oto-laryngologica. Supplementum·M BALSLEVJORGENSEN

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Citations

Dec 18, 2013·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Marzena Mielczarek, Jurek Olszewski
Dec 2, 2009·American Journal of Audiology·Tao PanStephanie A Gogel

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