PMID: 589842Aug 1, 1977

Electrocochleographic changes in acoustic neuroma: some experimental findings

Clinical Otolaryngology and Allied Sciences
H A BeagleyM C Remond

Abstract

Reversible experimental lesions were produced in the central end of the cochlear nerve at the IAM of guinea pigs by various procedures, including the instillation of KCl (0.1 or 0.01 M). As a result the usual diphasic AP waveforms seen in guinea pigs (when click stimuli are used) were transformed into monophasic, widened negative waves. This change, attributed to a neural block, was reversible, e.g. when the instilled KCl was dispersed by irrigation with normal saline. It is suggested that the widened monophasic negative AP's observed at ECochG in cases of acoustic neuroma or similar lesions, are produced in this way.

References

Nov 1, 1976·The Journal of the Acoustical Society of America·J J Eggermont
Jan 1, 1976·Clinical Otolaryngology and Allied Sciences·A W MorrisonH A Beagley
Feb 1, 1976·The Journal of Laryngology and Otology·W P Gibson, H A Beagley
Oct 1, 1974·The Journal of the Acoustical Society of America·J P Legouix, A Pierson
Jun 1, 1974·Acta Oto-laryngologica·E A Daigneault

Citations

Jan 1, 1986·Hearing Research·V F Prijs
Jul 17, 1998·The Laryngoscope·S LevineK A Daly
Jan 1, 1991·American Journal of Otolaryngology·M C Greiman, R P Lusk
Feb 9, 2017·Frontiers in Systems Neuroscience·J J Eggermont
Nov 1, 1980·The Annals of Otology, Rhinology & Laryngology. Supplement·J J EggermontD E Brackmann

Related Concepts

Acoustic Nerve
Nerve Impulses
Audiometry
Cochlear Structure
Differential Diagnosis
Cavia porcellus
Ménière's Vertigo
Neuroma, Acoustic, Unilateral

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