Electroencephalographic and electromyographic changes during the use of detomidine and detomidine-butorphanol combination in standing horses

Acta Veterinaria Hungarica
P Kruluc, Alenka Nemec

Abstract

Clinically, the use of detomidine and butorphanol is suitable for sedation and deepening of analgosedation. The aim of our study was to establish the influence of detomidine used alone and a butorphanol-detomidine combination on brain activity and to evaluate and compare brain responses (using electroencephalography, EEG) by recording SEF90 (spectral edge frequency 90%), individual brain wave fractions (beta, alpha, theta and delta) and electromyographic (EMG) changes in the left temporal muscle in standing horses. Ten clinically healthy cold-blooded horses were divided into two groups of five animals each. Group I received detomidine and Group II received detomidine followed by butorphanol 10 min later. SEF90, individual brain wave fractions and EMG were recorded with a pEEG (processed EEG) monitor using computerised processed electroencephalography and electromyography. The present study found that detomidine alone and the detomidine-butorphanol combination significantly reduced SEF90 and EMG, and they caused changes in individual brain wave fractions during sedation and particularly during analgosedation. The EMG results showed that the detomidine-butorphanol combination provided greater and longer muscle relaxation. Our EEG...Continue Reading

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Citations

Mar 28, 2012·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Mark HoyerMarno Wolters
Nov 23, 2011·Veterinary Anaesthesia and Analgesia·Simone K RingerRegula Bettschart-Wolfensberger
Jun 28, 2019·Frontiers in Veterinary Science·Henry S Adair, David Levine
Aug 28, 2021·Animals : an Open Access Journal From MDPI·Paola StraticòLucio Petrizzi

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