Electroencephalographic and neuroimaging findings in neonates undergoing extracorporeal membrane oxygenation

Neuropediatrics
J S HahnR W Coen

Abstract

Electroencephalograms (EEGs) were recorded on 36 infants who were treated with arteriovenous extracorporeal membrane oxygenation (ECMO) between 1986 and 1989. Twelve of 36 infants had EEGs prior to and during ECMO. Twenty-one infants who met ECMO criteria but were treated with mechanical ventilation only served as a comparison (COMP) group. Electrographic seizures occurred in 7 of the 36 (19%) ECMO patients and in 3 of the 21 (14%) COMP patients. Five of 7 ECMO infants had electrographic status epilepticus. Three infants developed electrographic seizures during ECMO in association with an acute cerebral injury. These patients did not have significant hemispheric predominance in the origin of electrographic seizures (2 right, 3 left and 2 bilateral). Repetitive or periodic discharges (RPD) with frequencies between 0.5 and 5 Hz were seen after starting therapy in 23 of the 36 (64%) ECMO patients and 15 of the 21 (71%) of the COMP group. Only in the ECMO patients did RPD arise significantly more frequently from the right hemisphere (13 right, 4 left and 6 bilateral; p = 0.015). Neuroimaging studies showed evidence of ischemic lesion in 8 of the 36 (22%) ECMO patients with significantly right-sided predominance (5 right, 1 left and...Continue Reading

Citations

Jan 22, 2013·Current Neurology and Neuroscience Reports·Nicholas S AbendUNKNOWN Pediatric Critical Care EEG Group (PCCEG) and the Critical Care EEG Monitoring Research Consortium (CCEMRC)
Apr 3, 2013·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Nicholas S AbendRobert R Clancy
Jul 5, 2013·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Juan A PiantinoJoshua Goldstein
Mar 4, 2014·Seminars in Perinatology·Arno F J van HeijstHanneke Ijsselstijn
Apr 2, 2015·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Melania M BembeaMichael V Johnston
May 11, 2015·The Journal of Thoracic and Cardiovascular Surgery·Maryam Y NaimNicholas S Abend
Jul 1, 2015·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Luella C GerritsKian D Liem
Feb 26, 2015·Seminars in Perinatology·An N Massaro
Jun 1, 2005·Seminars in Perinatology·Dorothy Bulas, Penny Glass
Jan 29, 2019·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Jane L Di GennaroDavid M McMullan
Aug 8, 2020·Journal of Clinical Medicine·Jordana FoxLakshmi Raman
Jan 19, 2017·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Jainn-Jim LinNicholas S Abend
Oct 29, 2020·Journal of Child Neurology·Sarah L Bauer HuangRéjean M Guerriero
Feb 6, 2018·Seminars in Perinatology·Nan LinDaniel J Licht

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