PMID: 16645442Apr 29, 2006Paper

Electroencephalographic approximate entropy changes in healthy volunteers during remifentanil infusion

Anesthesiology
Gyu-Jeong NohSteven E Kern

Abstract

The aim of this study was to investigate the independent effect of remifentanil on the approximate entropy (ApEn) in frontoparietal montages. The authors investigated which montages were relevant to assess the remifentanil effect on the electroencephalogram. Spectral edge frequency and the canonical univariate parameter were used as comparators. Twenty-eight healthy volunteers were enrolled. With recording of the electroencephalogram at the F3, F4, Cz, P3, and P4 montages, remifentanil was infused at the rate of 1-8 mug . kg . min for 15-20 min. The relation between remifentanil concentration and the electroencephalographic parameters were tested by Spearman correlation. Signal-to-noise ratio, artifact robustness, coefficient of variation of the median baseline and maximal electroencephalographic effects, and ratio of average maximal electroencephalographic effect to interindividual baseline variability were measured. The performance of ApEn as an index of remifentanil effect site concentrations was tested by prediction probability. Approximate entropy showed significant correlation (R = -0.6465, P < 0.0001) with remifentanil concentration. It provided comparable signal-to-noise ratio, artifact robustness, and ratio of average ...Continue Reading

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Citations

Jun 19, 2013·Naunyn-Schmiedeberg's Archives of Pharmacology·Jörn LötschBruno G Oertel
Sep 29, 2012·Clinical Pharmacokinetics·Bruno Georg OertelJörn Lötsch
May 15, 2009·Critical Care : the Official Journal of the Critical Care Forum·Anthony R Absalom, David K Menon
Aug 26, 2014·Journal of Pharmacokinetics and Pharmacodynamics·Soo-Han LeeGyu-Jeong Noh
Apr 19, 2013·British Journal of Clinical Pharmacology·Lasse Paludan MalverAsbjørn Mohr Drewes
Sep 25, 2014·Basic & Clinical Pharmacology & Toxicology·Carina GraversenAsbjørn M Drewes
Sep 18, 2014·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Ahmad Khodayari-RostamabadAsbjørn M Drewes
Aug 20, 2010·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Dong-Yu WuMao-Bin Wang
Mar 1, 2015·Journal of Pharmacokinetics and Pharmacodynamics·Byung-Moon ChoiGyu-Jeong Noh
May 8, 2013·Anesthesiology·Timothy T Houle, Dana P Turner
Jul 9, 2010·Anesthesiology·David T J LileyMichel M R F Struys
Oct 4, 2016·Clinical and Experimental Pharmacology & Physiology·SangMin ChoeGyu-Jeong Noh
Aug 30, 2017·Scandinavian Journal of Pain·Iben W FischerAnne E Olesen
Feb 5, 2021·The Journal of International Medical Research·Jian-Wen ZhangBao-Guo Wang
Jan 9, 2021·Journal of Pharmacokinetics and Pharmacodynamics·Kyung Mi KimJi-Yeon Bang
May 1, 2021·Frontiers in Aging Neuroscience·Dieu Ni Thi DoanJaeuk U Kim
Jul 11, 2007·Current Opinion in Anaesthesiology

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