Electrokinetics with blood

Electrophoresis
Suman Chakraborty

Abstract

Microfluidics based lab-on-a-chip technology holds tremendous promises towards point-of-care diagnosis of diseases as well as for developing engineered devices aimed towards replicating the intrinsic functionalities of human bodies as mediated by blood vessel mimicking circulatory networks. While the analysis of transport of blood including its unique cellular constituents has remained to be the focus of many reported studies, a progressive interest on understanding the interplay between electric field and blood flow dynamics has paved a new way towards further developments from scientific engineering as well as clinical viewpoint. Here, we briefly outline the interconnection between electrokinetics and blood flow through micro-capillaries, in an effort to address several challenging propositions in a wide variety of applications encompassing biophysical transport to medical diagnostics. We first present the fundamentals of interaction of electric field with cellular components. In conjunction with the unique rheological features of blood, we show that this interaction may turn out to be compelling for the use of electric fields for transporting blood samples through microfluidic conduits. We discuss the perspectives of both di...Continue Reading

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Citations

Feb 16, 2020·Electrophoresis·Boonchai TechaumnatYuji Suzuki
Mar 15, 2019·Biomicrofluidics·Golak KuntiSuman Chakraborty
Mar 15, 2019·Biomicrofluidics·Kiran Raj MSuman Chakraborty
Nov 6, 2020·Electrophoresis·Kel S Hakim, Blanca H Lapizco-Encinas
Oct 23, 2021·Journal of Physics. Condensed Matter : an Institute of Physics Journal·Ivan C Christov

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