Electrolyte changes after bowel preparation for colonoscopy: A randomized controlled multicenter trial

World Journal of Gastroenterology : WJG
Kyong Joo LeeHyun Il Seo

Abstract

To investigate the electrolyte changes between 2-L polyethylene glycol with ascorbic acid 20 g (PEG-Asc) and 4-L PEG solutions. From August 2012 to February 2013, a total of 226 patients were enrolled at four tertiary hospitals. All patients were randomly allocated to a PEG-Asc group or a 4-L PEG. Before colonoscopy, patients completed a questionnaire to assess bowel preparation-related symptoms, satisfaction, and willingness. Endoscopists assessed the bowel preparation using the Boston Bowel Preparation Scale (BBPS). In addition, blood tests, including serum electrolytes, serum osmolarity, and urine osmolarity were evaluated both before and after the procedure. A total of 226 patients were analyzed. BBPS scores were similar and the adequate bowel preparation rate (BBPS ≥ 6) was not different between the two groups (PEG-Asc vs 4-L PEG, 73.2% vs 76.3%, P = 0.760). Bowel preparation-related symptoms also were not different between the two groups. The taste of PEG-Asc was better (41.1% vs 16.7%, P < 0.001), and the willingness to undergo repeated bowel preparation was higher in the PEG-Asc group (73.2% vs 59.3%, P = 0.027) than in 4-L PEG. There were no significant changes in serum electrolytes in either group. In this multicenter...Continue Reading

References

Jun 1, 1995·Diseases of the Colon and Rectum·R W GolubP S Aguilar
Nov 4, 2000·Gastrointestinal Endoscopy·W H KimI S Park
May 1, 2001·Alimentary Pharmacology & Therapeutics·T K Toledo, J A DiPalma
Jun 23, 2001·The American Journal of Gastroenterology·R M NessN Chalasani
Sep 6, 2001·Diseases of the Colon and Rectum·J H Xing, E E Soffer
Jul 24, 2002·The American Journal of Gastroenterology·Douglas K RexL Lisa Bratcher
Jun 18, 2003·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Ann HayesDouglass Fuller
May 5, 2007·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·P O HendryR H Diament
Aug 30, 2008·Alimentary Pharmacology & Therapeutics·J BelseyD Heresbach
Dec 25, 2008·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Gary Lichtenstein
Jan 13, 2009·Gastrointestinal Endoscopy·Edwin J LaiBrian C Jacobson
Oct 21, 2009·Current Oncology Reports·R Scott Nelson, Alan G Thorson
Sep 9, 2011·European Journal of Gastroenterology & Hepatology·Sita V JansenCees Th B M van Deursen
Nov 29, 2011·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Flavio ValianteMichele De Boni
Jun 12, 2013·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Maurizio GentilePietro Forestieri
Jun 19, 2013·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Thierry PonchonMarc Halphen
Sep 21, 2013·The New England Journal of Medicine·Reiko NishiharaAndrew T Chan
Nov 1, 2005·Current Therapeutic Research, Clinical and Experimental·Stéphane MoulyJean-François Bergmann

❮ Previous
Next ❯

Citations

Mar 4, 2014·PloS One·Rong HuangTai-Hing Lam
May 10, 2019·Scientific Reports·Soo-Hyun LeeYoung-Sang Kim
Jul 19, 2016·Current Opinion in Gastroenterology·Theodor VoiosuRadu Voiosu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.