Electromechanical cell lysis using a portable audio device: enabling challenging sample preparation at the point-of-care

Lab on a Chip
J R BuserP Yager

Abstract

Audio sources are ubiquitously available on portable electronic devices, including cell phones. Here we demonstrate lysis of Mycobacterium marinum and Staphylococcus epidermidis bacteria utilizing a portable audio device coupled with a simple and inexpensive electromagnetic coil. The resulting alternating magnetic field rotates a magnet in a tube with the sample and glass beads, lysing the cells and enabling sample preparation for these bacteria anywhere there is a cell phone, mp3 player, laptop, or other device with a headphone jack.

References

Oct 3, 2006·Journal of Biochemical and Biophysical Methods·Hisatoshi KanekoTatsuo Suzutani
May 17, 2008·Biomedical Microdevices·Raymond Mariella
May 6, 2011·Journal of Clinical Microbiology·Peter E VandeventerAngelika Niemz
Jul 8, 2011·Lab on a Chip·Changchun LiuHaim H Bau
Jan 10, 2012·Analytical Chemistry·Vladimir GubalaDavid E Williams
Jun 27, 2012·Lab on a Chip·Brittany A Rohrman, Rebecca R Richards-Kortum
May 9, 2013·Lab on a Chip·Ali Kemal YetisenChristopher R Lowe
Nov 20, 2013·Analytical Chemistry·Bhushan J ToleyElain Fu

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Citations

Mar 28, 2017·Expert Review of Molecular Diagnostics·Luc Bissonnette, Michel G Bergeron
Jul 18, 2016·Journal of Microbiological Methods·Erin K HeinigerPaul Yager
Dec 4, 2015·Biotechnology Advances·Seokheun Choi
Oct 28, 2015·Lab on a Chip·J R BuserB H Weigl
Apr 24, 2018·The Analyst·Navjot Kaur, Bhushan J Toley
Nov 9, 2018·Scientific Reports·Hyun-Ju ParkMin-Young Lee

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