Electron ionization mass spectrometry as a tool for the investigation of the ortho effect in fragmentation of some Schiff bases derived from amphetamine analogs

Journal of Mass Spectrometry : JMS
Dariusz BłachutZbigniew Czarnocki

Abstract

The electron ionization-induced fragmentation patterns of three forensically relevant Schiff bases, originating from the condensation between 2-, 3- and 4-methoxyamphetamine and the corresponding ketones, were studied. The proposed fragmentation routes and ion structures are supported by high-resolution data and B/E linked-scan and mass-analyzed ion kinetic energy spectra. The rationalization of the ortho effect, which is responsible for the formation of the [M-OCH3] fragment in the case of the imine bearing ortho-substituted methoxy group, is given.

Citations

Jun 6, 2008·Journal of the American Society for Mass Spectrometry·Freneil B JariwalaAthula B Attygalle
Sep 10, 2019·Rapid Communications in Mass Spectrometry : RCM·Jiaxiang XuKezhi Jiang
Dec 12, 2017·Rapid Communications in Mass Spectrometry : RCM·Mengmeng ChenKezhi Jiang
Jun 15, 2005·Analytical Chemistry·T A BrettellR Saferstein

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