PMID: 7019667May 22, 1981Paper

Electron microscopic evidence of circular molecules in 9-S globin mRNA from rabbit reticulocytes

Molecular Biology Reports
A M LadhoffS Rosenthal

Abstract

9S globin mRNA prepared by the proteinase K method from polysomes of rabbit reticulocytes consists of 40% circular molecules as revealed by electron microscopy, if spreading of the molecules is performed from a solution of 50% formamide, 0.5 M NaCl, 25 mM Tris, 10 mM EDTA, pH 8, after 16 h incubation at 42 degrees C. We assume a noncovalent nature of the circularization because of the fact that a total transformation into the well known linear form occurs if strong denaturing conditions for spreading were used. The biological significance of the circular globin mRNA molecules is unknown.

References

Sep 1, 1978·Cell·H C HeindellW A Salser
Aug 1, 1976·European Journal of Biochemistry·H R Pelham, R J Jackson
Nov 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·H L SangerA K Kleinschmidt
Jul 16, 1973·European Journal of Biochemistry·J DubochetM Herzberg
Jan 1, 1969·Cold Spring Harbor Symposia on Quantitative Biology·C BaglioniM Jacobs-Lorena

❮ Previous
Next ❯

Citations

Oct 1, 1996·Plant Molecular Biology·J Fütterer, T Hohn
May 1, 1994·The International Journal of Biochemistry·H N RubinM N Halim
Jul 16, 1990·Gene·D Munroe, A Jacobson
Mar 4, 2008·Nucleic Acids Research·Gelina S KopeinaAlexander S Spirin
Jan 21, 1972·European Journal of Biochemistry·S PrehnS M Rapoport
Nov 9, 2001·Annual Review of Genetics·O Johnstone, P Lasko
Oct 23, 2008·Journal of the Association for Research in Otolaryngology : JARO·M Christian Brown, Douglas E Vetter
Jan 29, 2019·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Cody A Freas, Marcia L Spetch
Mar 31, 2019·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Kevin W ChristieAlbert S Feng
Nov 16, 2007·Die Naturwissenschaften·Paulo JorgeLuis Vicente
Sep 8, 2012·Die Naturwissenschaften·Lise DiezClaire Detrain
Mar 16, 2007·Die Naturwissenschaften·Martin Müller, Rüdiger Wehner
Oct 28, 2010·Die Naturwissenschaften·Francisco Javier Diego-RasillaJohn B Phillips
Sep 18, 2009·Die Naturwissenschaften·Wolfgang WiltschkoRoswitha Wiltschko
Jun 11, 2014·Die Naturwissenschaften·Ludmila OliveriusováFrantišek Sedláček
Nov 29, 2008·Die Naturwissenschaften·Ingo Schiffner, Roswitha Wiltschko
Apr 6, 2006·Die Naturwissenschaften·Wolfgang WiltschkoRoswitha Wiltschko
Sep 28, 2007·Die Naturwissenschaften·Sven GeiselhardtKlaus Peschke
Feb 11, 2014·Experimental Brain Research·Cheng-Chieh LinAlice Cronin-Golomb
May 12, 2005·Experimental Brain Research·Andrew D WilsonGeoffrey P Bingham
May 17, 2005·Experimental Brain Research·Andrew D WilsonGeoffrey P Bingham
Aug 9, 2007·Experimental Brain Research·Joeanna C ArthurDavid Chichka
Jun 6, 2007·Experimental Brain Research·Milena RaffiMaria Grazia Maioli
Apr 17, 2001·Journal of Motor Behavior·S F DonkerT Mulder
Apr 26, 2011·Experimental Brain Research·Erin V L Vasudevan, E Paul Zehr
Jun 7, 2008·Experimental Brain Research·Perrine Guerin, Benoît G Bardy
Jun 7, 2008·Experimental Brain Research·Vladimir Marlinski, Robert A McCrea
Aug 13, 2010·Experimental Brain Research·Andrew D WilsonGeoffrey P Bingham
Feb 9, 2010·Attention, Perception & Psychophysics·Piotr MajdakBernhard Laback
Aug 28, 2014·Nature·Emily M StandenHans C E Larsson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.