PMID: 108919Apr 1, 1979

Electron microscopical study of Neisseria meningitidis releasing various amounts of free endotoxin

Acta Pathologica Et Microbiologica Scandinavica. Section B, Microbiology
B M AndersenO Solberg

Abstract

A study has been made of the ultrastructure of four strains of Neisseria meningitidis which liberate varying amounts of free endotoxin in a chemically-defined, protein-free medium. The two strains which did not release detectable or only sparse amounts of free, filtrable endotoxin were rather uniform in cell size. Their cells appeared to be intact and showed a low tendency to aggregate, In addition cells of these strains showed only sporadic loose, trilaminar membranes and blebs, and free membranous structures were sparse in the medium. The endotoxin releasing strains liberated a high yield of free structures from the outer cell wall into the medium. These structures may represent the lipopolysaccharide (LPS).

References

Oct 1, 1977·Applied and Environmental Microbiology·K J SweadnerL L Nelsen
Jun 1, 1976·Antimicrobial Agents and Chemotherapy·W L Chin, J W Lawson
Dec 1, 1975·Canadian Journal of Microbiology·K G JohnsonR R Russel
Nov 1, 1973·The Journal of Experimental Medicine·I W Devoe, J E Gilchrist
Sep 1, 1974·Proceedings of the Society for Experimental Biology and Medicine·J H Jorgensen, R F Smith
Jul 1, 1973·The Journal of Infectious Diseases·J W Shands
Jul 1, 1972·Canadian Journal of Microbiology·C P KennyL Greenberg
Nov 1, 1972·Infection and Immunity·W D ZollingerM S Artenstein
Jun 3, 1967·Nature·M J CrutchleyJ Cameron
Jan 1, 1950·Proceedings of the Society for Experimental Biology and Medicine·J F MORGANR C PARKER

Related Concepts

Bacteriological Techniques
Plasma Membrane
Endotoxins
Limulus Test
Electron Microscopy
Neisseria meningitidis

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