Electron transfer and transport through multi-heme proteins: recent progress and future directions

Current Opinion in Chemical Biology
Jochen Blumberger

Abstract

I review recent experimental measurements probing electron transfer (ET) and electron transport (ETp) through multi-heme cytochromes (MHCs) as well as their theoretical interpretation. Examples include pump-probe spectroscopy of Ru-labeled MHCs aimed at determining heme-heme ET rates in MHCs and the measurement of the I-V characteristics of MHCs in bioelectronic junctions. While the ET mechanism appears to be well established for MHCs in aqueous solution, the ETp mechanism in bioelectronic junctions such as STM remains elusive partly due to the complexities of the electrode-protein interface.

Citations

Feb 23, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Faiza RasheedEva Johansson
Feb 14, 2019·Proceedings of the National Academy of Sciences of the United States of America·Xiuyun JiangJochen Blumberger
Feb 3, 2021·The Journal of Physical Chemistry. B·H Christopher FryAndrew L Ferguson
Apr 11, 2021·Proceedings of the National Academy of Sciences of the United States of America·Stanislav ZálišAntonín Vlček
May 18, 2021·ACS Nano·Kevin M Rosso, Piotr Zarzycki
Aug 28, 2019·Journal of the American Chemical Society·Jessica H van WonderenJulea N Butt
Nov 4, 2020·The Journal of Physical Chemistry Letters·Zdenek FuteraJochen Blumberger
Dec 13, 2018·Journal of Chemical Theory and Computation·Zdenek Futera, Jochen Blumberger
Sep 25, 2021·Proceedings of the National Academy of Sciences of the United States of America·Jessica H van WonderenJulea N Butt
Oct 30, 2021·Chemical Reviews·Samantha R McCuskeyThuc-Quyen Nguyen

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