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Electron transfer mediated electrochemical biosensor for microRNAs detection based on metal ion functionalized titanium phosphate nanospheres at attomole level

ACS Applied Materials & Interfaces

Jan 15, 2015

Fang-Fang ChengJun-Jie Zhu

Abstract

MicroRNAs (miRNAs) have emerged as new candidates as diagnostic and prognostic biomarkers for the detection of a wide variety of cancers; thus, sensitive and selective detection of microRNAs is significant for early-phase cancer diagnosis and disease prevention. A novel and simple elect...read more

Mentioned in this Paper

Titanium phosphate (4: 3)
Exertion
Electrochemical Techniques
Biosensors
Electron Transport
Neoplasms
RNA, Small Temporal
Phosphate Measurement
Cadmium Measurement
Molecular Profiling
1
37
Paper Details
References
  • References14
  • Citations16
12
  • References14
  • Citations16
12

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Electron transfer mediated electrochemical biosensor for microRNAs detection based on metal ion functionalized titanium phosphate nanospheres at attomole level

ACS Applied Materials & Interfaces

Jan 15, 2015

Fang-Fang ChengJun-Jie Zhu

PMID: 25588109

DOI: 10.1021/am508690x

Abstract

MicroRNAs (miRNAs) have emerged as new candidates as diagnostic and prognostic biomarkers for the detection of a wide variety of cancers; thus, sensitive and selective detection of microRNAs is significant for early-phase cancer diagnosis and disease prevention. A novel and simple elect...read more

Mentioned in this Paper

Titanium phosphate (4: 3)
Exertion
Electrochemical Techniques
Biosensors
Electron Transport
Neoplasms
RNA, Small Temporal
Phosphate Measurement
Cadmium Measurement
Molecular Profiling
1
37

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Biosensors for Cancer Detection

Biosensors are devices that are designed to detect a specific biological analyte by essentially converting a biological entity (ie, protein, DNA, RNA) into an electrical signal that can be detected and analyzed. The use of biosensors in cancer detection and monitoring holds vast potential. Biosensors can be designed to detect emerging cancer biomarkers and to determine drug effectiveness at various target sites. Biosensor technology has the potential to provide fast and accurate detection, reliable imaging of cancer cells, and monitoring of angiogenesis and cancer metastasis, and the ability to determine the effectiveness of anticancer chemotherapy agents.

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Paper Details
References
  • References14
  • Citations16
12
  • References14
  • Citations16
12
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