Electronic brachytherapy--current status and future directions

The British Journal of Radiology
D J Eaton

Abstract

In the past decade, electronic brachytherapy (EB) has emerged as an attractive modality for the treatment of skin lesions and intraoperative partial breast irradiation, as well as finding wider applications in intracavitary and interstitial sites. These miniature X-ray sources, which operate at low kilovoltage energies (<100 kV), have reduced shielding requirements and inherent portability, therefore can be used outside the traditional realms of the radiotherapy department. However, steep dose gradients and increased sensitivity to inhomogeneities challenge accurate dosimetry. Secondly, ease of use does not mitigate the need for close involvement by medical physics experts and consultant oncologists. Finally, further studies are needed to relate the more heterogeneous dose distributions to clinical outcomes. With these provisos, the practical convenience of EB strongly suggests that it will become an established option for selected patients, not only in radiotherapy departments but also in a range of operating theatres and clinics around the world.

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Citations

Feb 1, 2019·The Journal of Dermatological Treatment·Ali PashazadehMichael Friebe
Jan 25, 2020·Journal of Applied Clinical Medical Physics·Mubin Y ShaikhJay Burmeister
Jun 12, 2019·Journal of Applied Clinical Medical Physics·Sergio Lozares-CorderoVíctor González-Pérez
Mar 3, 2017·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·Blanca Ibanez-RoselloJose Perez-Calatayud
May 21, 2020·Nanomaterials·Kirill V MorozovVladimir N Morozov
Feb 15, 2017·Radiation Oncology·Frank W Hensley
Apr 11, 2018·Frontiers in Oncology·Anil SethiTarita O Thomas
Jan 20, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Sergio LozaresPatricia Rubio
Aug 18, 2020·Nanomedicine : Nanotechnology, Biology, and Medicine·Gilnaz OmyanFaraz Kalantari
Jan 12, 2021·Physics in Medicine and Biology·Daniel S BadaliTobias Funk
Mar 11, 2021·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·Xuesong DaiBing Li
Apr 27, 2021·Physical and Engineering Sciences in Medicine·Robin HillClive Baldock
Jul 3, 2021·International Journal of Molecular Sciences·Maria A KolyvanovaVladimir N Morozov

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