Electronic pancreatoscopy for the diagnosis of pancreatic diseases

The American Journal of Gastroenterology
Tadashi KodamaHisakazu Yamagishi

Abstract

Diagnostic pancreatoscopy was performed in 56 patients using the newly developed peroral electronic pancreatoscope (PEPS). The diagnostic value of the PEPS for pancreatic diseases was evaluated. The PEPS (external diameter = 2.1 mm, bidirectional tip deflection) was developed with a minute 50,000-pixel interline charge-coupled device. Pancreatoscopy was performed by means of an endoscopic retrograde approach without sphincterotomy. The cases examined were normal (three), chronic pancreatitis (32), pancreatic cancer (eight), and intraductal papillary mucinous tumors (13). Of the 56 cases, 42 (75%) were adequately seen. In normal cases, fine capillary vessels were clearly visualized on the smooth whitish-pink mucosa. Findings in chronic pancreatitis included protein plugs, calcified stones, rough whitish mucosa, scar formation, edema, erythema, and indistinct capillary appearance. All the stenoses of chronic pancreatitis could be differentiated from those of pancreatic cancer with the PEPS. In the pancreatic cancer cases, all patients had stenoses or duct cutoffs; most cases had friable mucosa with erythema and erosive changes, and a single patient had a compressed pancreatic duct wall covered with normal epithelium. In the cases...Continue Reading

References

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Citations

May 29, 2008·World Journal of Gastroenterology : WJG·Joel R Judah, Peter V Draganov
Jan 10, 2003·Journal of Gastroenterology and Hepatology·Tadashi KodamaHisakazu Yamagishi
Oct 30, 2009·Gastrointestinal Endoscopy·Nam Q NguyenJanak N Shah
Apr 16, 2004·Pancreas·Naotaka FujitaKei Ito
May 31, 2018·Current Opinion in Gastroenterology·Corey S Miller, Yen-I Chen
Apr 23, 2009·Journal of Gastroenterology and Hepatology·Nam Q Nguyen
Apr 10, 2007·Current Gastroenterology Reports·Yang K Chen
May 18, 2011·Hospital Practice·Geetha NallamothuDouglas G Adler
Feb 11, 2005·Current Opinion in Gastroenterology·Matthew J DiMagno, Eugene P DiMagno
Feb 2, 2019·World Journal of Gastrointestinal Endoscopy·Luca De LucaBenedetto Mangiavillano
Apr 29, 2015·World Journal of Gastroenterology : WJG·Mohan RamchandaniChristopher Khor
Jul 16, 2013·Current Opinion in Gastroenterology·Tolga ErimDouglas K Pleskow
Feb 23, 2019·World Journal of Gastrointestinal Endoscopy·Tarun KauraSaurabh Chawla

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