Electrophoretic bimorphism of serum albumin in the presence of indocyanine green

Journal of Chromatography
T J Muckle

Abstract

The presence of indocyanine green during extended traditional electrophoresis and immunoelectrophoresis of serum is associated with bimorphism of albumin. This occurs over a range of dye--albumin molar ratios an order or more greater than was obtained in similar phenomena described previously. The bimorphism seems not to be dose dependent beyond a certain point, and the two albumins so separated show tinctorial differences. The phenomenon has been observed to apparently the same degree in all normal sera tested, and may represent a means of distinguishing ligand-loaded and ligand-light serum albumin.

References

Feb 16, 1976·Clinica Chimica Acta; International Journal of Clinical Chemistry·J A Edwards, T J Muckle
Feb 15, 1977·Clinica Chimica Acta; International Journal of Clinical Chemistry·L BergeronM Page
Feb 1, 1976·Biochemical Medicine·T J Muckle
Sep 6, 1976·Clinica Chimica Acta; International Journal of Clinical Chemistry·D J Birkett, J Kapitulnik
Aug 16, 1976·Clinica Chimica Acta; International Journal of Clinical Chemistry·J RousseauxG Biserte
Apr 19, 1973·Clinica Chimica Acta; International Journal of Clinical Chemistry·T Kawaguchi
Nov 26, 1973·Annals of the New York Academy of Sciences·A A SpectorJ E Fletcher
Apr 19, 1973·Clinica Chimica Acta; International Journal of Clinical Chemistry·T Kawaguchi
Apr 1, 1973·Annals of Human Genetics·L R WeitkampA L Tárnoky
Jan 1, 1970·Advances in Clinical Chemistry·T Peters
Apr 4, 1970·British Medical Journal·B J Stoodley, D J Rowe
Aug 1, 1970·Clinica Chimica Acta; International Journal of Clinical Chemistry·R Starinsky, E Shafrir
Oct 1, 1968·Clinica Chimica Acta; International Journal of Clinical Chemistry·D A ArvanL Melartin
Jan 1, 1968·Scandinavian Journal of Clinical and Laboratory Investigation·O J Bjerrum
Aug 1, 1966·Proceedings of the Society for Experimental Biology and Medicine·K J Baker
Apr 1, 1953·Archives of Biochemistry and Biophysics·U WESTPHALS G PRIEST

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