PMID: 3767078Jan 1, 1986Paper

Electrophoretic polymorphism and molecular structure of equine C3

Animal Genetics
P H KayD Bernoco

Abstract

Plasma or serum samples from 12 Arabian and 181 standardbred horses have been typed using an immunofixation technique to determine electrophoretic polymorphism of equine third complement component (C3). Six distinctly different electrophoretic patterns of equine C3 have been recognized thus far. SDS PAGE analysis of equine C3/anti C3 complexes revealed that the submolecular structure comprised an alpha chain and beta chain of molecular weights approximately 118,000 and 63,000 daltons respectively. The molecular weights of the alpha and beta chains were similar in all electrophoretic variants tested. Family data derived from 73 mares, 21 stallions and 99 offspring suggested that the six electrophoretic phenotypes were inherited by means of three codominant alleles named C3-1, C3-2 and C3-3 at a single autosomal locus.

References

Aug 1, 1979·Journal of Immunogenetics·R R de VriesJ J van Rood
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Oct 1, 1980·Acta Neurologica Scandinavica·H Jans, H Sørensen

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Citations

Sep 1, 1993·Veterinary Immunology and Immunopathology·J S Boschwitz, J F Timoney
Jul 18, 2001·Veterinary Immunology and Immunopathology·G GröndahlK Nilsson Ekdahl
Jan 1, 1990·Animal Genetics·A T Bowling, S Dileanis
Jan 1, 1989·Animal Genetics·R K JunejaB Gahne

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