Abstract
Local ventricular activation time and the conduction time during sinus rhythm at the induction of ventricular tachycardia (VT) and ventricular fibrillation (VF) were investigated using a canine model of chronic myocardial infarction. Of 26 dogs studied, 15 had inducible VT, 10 had inducible VF, and 1 had no inducible arrhythmias. Bipolar local ventricular electrograms were recorded during sinus rhythm from 136 sites in 10 dogs with VT and 164 sites in 11 dogs with VF. Mean activation time in dogs with inducible VT was significantly longer than in dogs with inducible VF. Furthermore, simultaneous local ventricular electrograms were recorded during the induction of VT (74 episodes) or VF (38 episodes) from the infarct border zone at the endocardium (B-EN), the epicardium (B-EP), and normal sites (N-EN, N-EP). During VT induction, the activation time at N-EN and N-EP was significantly longer than during VF induction (N-EN: 94 +/- 21, 70 +/- 19 ms; N-EP: 83 +/- 21, 64 +/- 10 ms; p < 0.05). Conduction time was measured at the initiation of VT or VF induced by orthodromic or antidromic pacing. The conduction times of the last paced beat between N-EN and B-EP (35 +/- 11, 62 +/- 24 ms), N-EN and N-EP (35 +/- 12, 14 +/- 13 ms), B-EN and...Continue Reading
References
Dec 1, 1978·The American Journal of Cardiology·S R SpielmanM E Josephson
Apr 1, 1992·Circulation·B AvitallP Tchou
May 1, 1988·Pacing and Clinical Electrophysiology : PACE·P L PagéM Shenasa
Jun 1, 1989·Journal of the American College of Cardiology·S M DaileyV J Plumb
Jan 1, 1989·Circulation Research·A R DennissJ B Uther
Feb 1, 1988·Journal of the American College of Cardiology·A R DennissJ B Uther
Mar 1, 1987·The American Journal of Cardiology·A R DennissJ B Uther
Apr 1, 1986·Circulation·D M CassidyM E Josephson
Apr 1, 1986·Journal of the American College of Cardiology·H S KaragueuzianT Peter
Mar 1, 1985·The American Journal of Cardiology·D M CassidyM E Josephson
May 1, 1985·Journal of the American College of Cardiology·H GaranG Grant
May 1, 1985·The American Journal of Cardiology·R A FreedmanJ W Mason
Jun 1, 1985·The American Journal of Cardiology·J B AgarwalR H Helfant
Sep 1, 1985·Circulation Research·W B GoughN el-Sherif
Nov 1, 1983·The American Journal of Cardiology·D S EchtJ W Mason
Feb 1, 1984·Circulation·D A RichardsE N Moore
May 1, 1984·American Heart Journal·F MoradyM M Scheinman
Aug 1, 1984·The Journal of Clinical Investigation·H Garan, J N Ruskin
Nov 1, 1980·Circulation·H GaranJ N Ruskin
Apr 1, 1981·Circulation·E L MichelsonE N Moore