PMID: 11345381May 10, 2001Paper

Electrophysiologic characteristics in initiation of paroxysmal atrial fibrillation from a focal area

Journal of the American College of Cardiology
T M LuS A Chen

Abstract

We investigated the electrophysiologic characteristics in the initiation of paroxysmal atrial fibrillation (PAF) from a focal area. The electrophysiologic characteristics in the initiation of PAF are still not clear. The study group consisted of 77 patients (M/F = 65/12, age 66 +/- 12 years) with frequent episodes of PAF; we analyzed: 1) 15 cycle lengths of electrical activity before the onset of atrial fibrillation (AF); 2) coupling interval (CI) of the first ectopic beat just before the initiation of AF; and 3) the prematurity of an ectopic beat (prematurity index [PI] = CI/mean of preceding 15 cycle lengths). A total of 111 episodes of sustained AF were identified. Two patterns of AF initiation were observed: group I (59/111, 53%) included the episodes preceded by cycle length oscillation, and group II (52/111, 47%) included the episodes initiated by a single ectopic beat with preceding cycle length relatively constant. The PI of group I episodes was significantly greater than that of group II (0.41 +/- 0.12 vs. 0.34 +/- 0.10, p < 0.01). The CI (267 +/- 54 ms vs. 217 +/- 55 ms, p < 0.05), AF1 (194 +/- 36 ms vs. 153 +/- 37 ms, p < 0.05) and PI (0.49 +/- 0.13 vs. 0.37 +/- 0.11, p < 0.01) of the AF episodes from the superior ve...Continue Reading

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Citations

Nov 5, 2004·Basic Research in Cardiology·Shih-Huang LeeShih-Ann Chen
Mar 29, 2006·Basic Research in Cardiology·Hung-I YehCheng-Ho Tsai
Jun 26, 2003·Pacing and Clinical Electrophysiology : PACE·Yves GuyomarPierre Graux
Dec 6, 2007·Circulation Journal : Official Journal of the Japanese Circulation Society·Yi-Jen Chen, Shih-Ann Chen
Apr 14, 2004·Pacing and Clinical Electrophysiology : PACE·Thomas J JensenBloch Thomsen
Jan 19, 2007·Journal of Cardiovascular Electrophysiology·Jing ZhouSunny S Po
Oct 28, 2008·Pacing and Clinical Electrophysiology : PACE·Mirela OvreiuC Allen Bashour
Oct 30, 2004·Pacing and Clinical Electrophysiology : PACE·Owen ObelDavid Keane
Mar 25, 2017·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·David G JonesNicholas S Peters
Feb 6, 2019·Journal of Cardiovascular Medicine·Massimo MagnanoMatteo Anselmino
Jun 27, 2006·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Paolo AzzoliniAndrea Puglisi
Jul 31, 2013·Expert Review of Cardiovascular Therapy·Sunil K Agarwal, Elsayed Z Soliman

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