May 1, 1995

Electrophysiologic determinants of ventricular rate in human atrial fibrillation

Journal of Cardiovascular Electrophysiology
Y AsanoH Matsuo

Abstract

The mechanisms of the ventricular response during atrial fibrillation (AF) remain uncertain. The parameters obtained during an electrophysiologic study, including atrial rates during AF, were analyzed to clarify further the determinants of the ventricular rate during AF. Thirty patients without manifest preexcitation in whom AF was induced during electrophysiologic study were divided into two groups. Group 1 consisted of 20 patients (ages 55 +/- 10 years) without a dual AV nodal pathway. Group 2 consisted of 10 patients (ages 53 +/- 13 years) having a dual AV nodal pathway. The correlation coefficient between the mean RR interval during AF (mRR) and the mean intra-atrial potential interval during AF (mff) was positive (0.05 [P < 0.05] in group 1 and 0.37 [P = NS] in group 2). The correlation coefficient of the mRR against the functional refractory periods of the AV node (AVFRP) was 0.73 (P < 0.001) in group 1. The correlation coefficients between mRR and the fast AV nodal pathway functional refractory periods and the slow AV nodal pathway effective refractory periods (SPERP) were 0.58 (P = NS) and 0.7 (P < 0.05) in group 2, respectively. The correlation coefficients between mRR against (mff x AVFRP)1/2 in group 1 and (mff x SPE...Continue Reading

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Mentioned in this Paper

Sinoatrial Node
Refractory Period, Electrophysiological
Atrial Fibrillation
Hyperbilirubinemia, Neonatal
Cardiac Conduction System
Structure of Atrioventricular Node
Electrophysiology (Science)
Ventricular Function
Cardiac Pacing, Artificial
NODAL

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