PMID: 16502364Feb 28, 2006Paper

Electrophysiological and echocardiographic parameters predisposing to atrial fibrillation in patients with a structurally normal heart

Kardiologia polska
Dragos CozmaStefan-Iosif Dragulescu

Abstract

The electroanatomical substrate of dilated atria is characterised by increased non-uniform anisotropy and macroscopic slowing of conduction, which promote reentrant circuits. To analyse the relationship between electrophysiological properties of atria and echocardiographic markers of dilatation and increased filling pressure. The study group consisted of 79 patients without structural heart disease, aged 53+/-22 years, who were referred for electrophysiological study. In order to examine the atrial electrophysiological characteristics we studied interatrial conduction time (iaCT), double potentials and fragmented atrial activity during premature stimulation of the high right atrium (HRA). The analysed parameters included: duration of atrial activity, baseline iaCT (iaCTb) between HRA and distal coronary sinus (CS), iaCT during HRA pacing S1S1 600 ms (iaCTS1), maximum prolongation of iaCT during S2 and S3 delivery (iaCTS2, iaCTS3). We also calculated the decremental index (DI)=iaCT S3- iaCTS1/iaCTS1%. The following echocardiographic parameters were assessed: left atrial (LA) dimensions, surface (LAs), volume using ellipse formula (LAv), right surface (RAs), total atrial surface (TAs=LAs+RAs), and global myocardial index (GMI). P...Continue Reading

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