Electrophysiological Correlates of Semantic Dissimilarity Reflect the Comprehension of Natural, Narrative Speech

Current Biology : CB
Michael P BroderickEdmund C Lalor

Abstract

People routinely hear and understand speech at rates of 120-200 words per minute [1, 2]. Thus, speech comprehension must involve rapid, online neural mechanisms that process words' meanings in an approximately time-locked fashion. However, electrophysiological evidence for such time-locked processing has been lacking for continuous speech. Although valuable insights into semantic processing have been provided by the "N400 component" of the event-related potential [3-6], this literature has been dominated by paradigms using incongruous words within specially constructed sentences, with less emphasis on natural, narrative speech comprehension. Building on the discovery that cortical activity "tracks" the dynamics of running speech [7-9] and psycholinguistic work demonstrating [10-12] and modeling [13-15] how context impacts on word processing, we describe a new approach for deriving an electrophysiological correlate of natural speech comprehension. We used a computational model [16] to quantify the meaning carried by words based on how semantically dissimilar they were to their preceding context and then regressed this measure against electroencephalographic (EEG) data recorded from subjects as they listened to narrative speech. ...Continue Reading

Citations

Sep 4, 2019·Journal of Cognitive Neuroscience·Hugo WeissbartTobias Reichenbach
Dec 17, 2019·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Mante S NieuwlandSarah Von Grebmer Zu Wolfsthurn
Jan 28, 2020·Journal of Neural Engineering·K V DijkstraP W M Desain
Aug 23, 2018·Frontiers in Neuroscience·Daniel D E WongAlain de Cheveigné
Jun 5, 2019·Scientific Reports·Andrea OlguinMirjana Bozic
Aug 28, 2020·PLoS Biology·Florian DestokyMathieu Bourguignon
Sep 11, 2019·Journal of Neural Engineering·Zhen FuJing Chen
Mar 3, 2020·International Journal of Neural Systems·Yongjie ZhuFengyu Cong
Jul 22, 2018·Language, Cognition and Neuroscience·Liberty S Hamilton, Alexander G Huth
Apr 6, 2019·Journal of Speech, Language, and Hearing Research : JSLHR·Zilong XieBharath Chandrasekaran
Feb 26, 2019·Nature Communications·Sasa L KivisaariRiitta Salmelin
Mar 4, 2020·ELife·Giovanni M Di LibertoNima Mesgarani
Aug 30, 2018·Frontiers in Neuroscience·Nicholas HuangMounya Elhilali
May 16, 2020·Frontiers in Human Neuroscience·Shyanthony R SynigalEdmund C Lalor
Jul 4, 2020·Language, Cognition and Neuroscience·Shaorong Yan, T Florian Jaeger
Aug 6, 2020·The Journal of the Acoustical Society of America·Jieun SongPaul Iverson
Dec 22, 2020·NeuroImage·Giovanni M Di LibertoNima Mesgarani
Dec 7, 2019·Neuron·Peter W Donhauser, Sylvain Baillet
May 18, 2020·NeuroImage·Christian PfeifferNicolas Langer
Mar 22, 2021·NeuroImage·Paul de LangeMathieu Bourguignon
Apr 17, 2019·NeuroImage·Giovanni M Di LibertoAlain de Cheveigné
Apr 17, 2021·The European Journal of Neuroscience·Jana Van CanneytTom Francart
Apr 20, 2021·Frontiers in Neuroscience·Juraj MesikMagdalena Wojtczak
May 5, 2021·ELife·Paz Har-Shai Yahav, Elana Zion Golumbic
Jul 24, 2021·Cerebral Cortex Communications·Tomas LencSylvie Nozaradan
Nov 24, 2020·Current Opinion in Physiology·Christian Brodbeck, Jonathan Z Simon
Sep 7, 2021·Journal of Anatomy·Charles TaylorScott Border

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.