Electrophysiological mechanisms of spontaneous termination of sustained monomorphic reentrant ventricular tachycardia in the canine postinfarction heart

Circulation
N el-SherifM Restivo

Abstract

The electrophysiological mechanisms of spontaneous termination of sustained monomorphic ventricular tachycardia (SMVT), in the postinfarction heart, generally considered secondary to a reentrant mechanism, have not been fully investigated. Epicardial activation maps of spontaneous termination of 20 different episodes of SMVT (lasting 30 seconds to 10 minutes) from 8 dogs, 4 to 5 days after one-stage ligation of the left anterior descending coronary artery, were analyzed with the use of 254 bipolar electrode recordings with high density (2.5 to 2.8 mm between bipolar electrodes) in the ischemic zone. All ventricular tachycardias (VTs) were due to circus movement reentry with a characteristic figure-8 configuration. Termination always occurred when the two circulating wave fronts blocked in the central common pathway (CCP). Two basic mechanisms of spontaneous termination were observed: (1) In 15 episodes, acceleration of conduction occurred in parts of the reentrant circuit and was associated with slowing of conduction and finally conduction block in the CCP. Acceleration of conduction occurred in the last few cycles of VT both at the outer border of the arcs of functional conduction block in the "normal" myocardial zone and at t...Continue Reading

References

Nov 1, 1994·Journal of Cardiovascular Electrophysiology·J M DavidenkoJ Jalife

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Citations

Oct 15, 1987·Experientia·B F Hoffman, K H Dangman
Feb 17, 1999·Pacing and Clinical Electrophysiology : PACE·V S PrakashS A Chen
Sep 1, 2009·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Herman D HimelNabil El-Sherif
Jul 5, 2005·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Frank BogunFred Morady
Oct 11, 2005·American Journal of Physiology. Heart and Circulatory Physiology·William R MillsKenneth R Laurita

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