Electrospinning, mechanical properties, and cell behavior study of chitosan/PVA nanofibers

Journal of Biomedical Materials Research. Part a
Mojtaba Koosha, Hamid Mirzadeh

Abstract

Electrospinning process has been widely used to produce nanofibers from polymer blends. Poly(vinyl alcohol) (PVA) and chitosan (CS) have numerous biomedical applications such as wound healing and tissue engineering. Nanofibers of CS/PVA have been prepared by many works, however, a complete physicochemical and mechanical characterization as well as cell behavior has not been reported. In this study, PVA and CS/PVA blend solutions in acetic acid 70% with different volume ratios (30/70, 50/50, and 70/30) were electrospun in constant electrospinning process parameters. The structure and morphology of nanofibrous mats were characterized by SEM, FTIR, and XRD methods. The best nanofibrous mat was achieved from the CS/PVA 30/70 blend solution regarding the electrospinning throughput. The dynamic mechanical thermal analysis (DMTA) of PVA and CS/PVA 30/70 nanofibrous mats were measured which were not considered in the previous studies. DMTA results in accordance to the DSC analysis approved the partial compatibility between the two polymers, while a single glass transition temperature was not observed for the blend. The tensile strength of PVA and CS/PVA nanofibers were also reported. Results of cell behavior study indicated that the he...Continue Reading

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Citations

Jun 27, 2015·Journal of Biomedical Materials Research. Part a·Shahrzad FathollahipourMojtaba Koosha
Feb 18, 2016·Journal of Biomedical Materials Research. Part a·Samaneh Moghadasi BoroujeniMasoud Soleimani
Mar 4, 2017·Journal of Biomedical Materials Research. Part a·Asma S MotamediMohammad A Shokrgozar
May 24, 2017·Journal of Agricultural and Food Chemistry·Peng WenHong Wu
Feb 13, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Maria Justina Roxana VirlanMaria Greabu
Sep 29, 2017·Journal of Materials Science. Materials in Medicine·Dariush SemnaniMehrnoosh Maherolnaghsh
Jun 1, 2018·Nanomaterials·Md Nahid Pervez, George K Stylios
May 5, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Mohammad-Ali ShahbaziAlireza Dolatshahi-Pirouz
May 14, 2020·Expert Opinion on Drug Delivery·Maurício G C SousaOctávio L Franco
Oct 30, 2019·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Xize GaoJun Wu
Jun 17, 2020·Journal of Biophotonics·Alessio MilanesiRoberto Pini
Sep 23, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Sergio Pineda-CastilloLukas Munster
Sep 6, 2019·Annals of Biomedical Engineering·Abinash Padhi, Amrinder S Nain
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Sep 28, 2017·Journal of Agricultural and Food Chemistry·Peng WenHong Wu
Aug 28, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jorge Iván CastroCarlos David Grande-Tovar
Aug 30, 2021·Journal of Materials Science. Materials in Medicine·Sadjad KhosravimelalMazaher Gholipourmalekabadi
Nov 18, 2021·Advanced Healthcare Materials·Liszt Y C Madruga, Matt J Kipper

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