Electrospray ionization mass spectrometry of metalloporphyrins

Journal of Mass Spectrometry : JMS
V E Vandell, P A Limbach

Abstract

The magnesium, nickel, copper, zinc and vanadium metalloporphyrins from octaethylporphyrin, etioporphyrin I and tetraphenylporphyrin were characterized using electrospray ionization mass spectrometry (ESI-MS). The ion abundance of each of the porphyrins present in binary mixtures was monitored as a function of the porphyrin concentration and is dependent on the metalloporphyrin oxidation potential. It was found that, for binary mixtures of metalloporphyrins whose oxidation potentials differ by less than 0.1 V, the resulting ion abundance of each species is directly proportional to the concentration of each analyte in the mixture. For binary mixtures whose oxidation potentials differ by more than 0.1 V, relative abundances of the radical cations of each metalloporphyrin are determined by the oxidation potential and concentration of each metalloporphyrin with the analyte of lowest oxidation potential being ionized preferentially. The ability to ionize selectively one porphyrin over another in a binary mixture offers the potential to use ESI-MS for the qualitative analysis of porphyrins present in complex mixtures.

Citations

Jun 13, 2009·Journal of Mass Spectrometry : JMS·Ricardo VessecchiSérgio E Galembeck
Dec 19, 2002·Journal of Mass Spectrometry : JMS·Janina Witowska-JaroszMaciej Jarosz
Oct 27, 2015·The Journal of Physical Chemistry. a·Ina D KellnerThomas Drewello
May 8, 2013·Rapid Communications in Mass Spectrometry : RCM·Misjudeen RajiAbdel-Hamid Emwas
Dec 31, 2010·Rapid Communications in Mass Spectrometry : RCM·Iriux AlmodóvarRamiro Araya-Maturana
Jul 18, 2015·The Journal of Physical Chemistry. a·Allyson M BuytendykKit H Bowen
Sep 18, 2010·Chemical Communications : Chem Comm·Malgorzata A Kaczorowska, Helen J Cooper
Sep 6, 2000·Journal of Mass Spectrometry : JMS·J F MoraJ B Fenn
May 29, 2000·Rapid Communications in Mass Spectrometry : RCM·Y Wu, H Wang
Apr 5, 2001·Journal of Mass Spectrometry : JMS·V Kertesz, G J Van Berkel
Dec 18, 2001·Journal of Mass Spectrometry : JMS·G J Van Berkel, V Kertesz
Oct 26, 2005·Journal of the American Society for Mass Spectrometry·Kimberly S F LauChristian Brückner
Jul 22, 2006·Journal of the American Society for Mass Spectrometry·Kimberly S F LauChristian Brückner
Jul 31, 2013·The Analyst·Pengyuan LiuHao Chen
Dec 1, 1999·Analytical Chemistry·G J Van BerkelL J Gray
Dec 18, 2002·Journal of the American Society for Mass Spectrometry·M Rosario M DominguesMichael L Gross

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.