Electrospun gelatin fiber mats containing a herbal-Centella asiatica-extract and release characteristic of asiaticoside

Panprung SikareepaisanPitt Supaphol


Ultra-fine gelatin (type A, porcine skin, ∼180 Bloom) fiber mats containing a methanolic crude extract of Centella asiatica (L.) Urban, a medicinal plant widely known for its traditional medical applications including its wound healing ability, were fabricated, for the first time, from the neat gelatin solution (22% w/v in 70 vol% acetic acid) containing the crude extract (mCA) in various amounts (i.e. 5-30 wt% based on the weight of gelatin powder) by electrospinning. Incorporation of mCA in the neat gelatin solution did not affect both the morphology and the size of the mCA-loaded gelatin fibers, as both of the neat and the mCA-loaded gelatin fibers were smooth and the average diameters of these fibers ranged between 226 and 232 nm. The cross-linked mCA-loaded e-spun gelatin fiber mat from the neat gelatin solution containing 30 wt% of mCA was further investigated for the release characteristic of asiaticoside, identified as the most active compound associated with the healing of wounds, in two different types of releasing medium, i.e. acetate buffer and the buffer containing 10 vol% of methanol, based on the thin-layer chromatography (TLC)-densitometry technique. Based on the unit weight of the actual amount of asiaticoside ...Continue Reading


Jan 1, 1980·Journal of Biomedical Materials Research·I V Yannas, J F Burke
Mar 1, 1980·Journal of Biomedical Materials Research·I V YannasR H Rubenstein
Apr 6, 1999·Phytotherapy Research : PTR·A ShuklaB N Dhawan
May 5, 2001·Biomaterials·K UlubayramN Hasirci
May 7, 2002·Journal of Controlled Release : Official Journal of the Controlled Release Society·El-Refaie KenawyGary E Wnek
Mar 17, 2004·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·J Vandervoort, A Ludwig
May 17, 2005·Biomaterials·Mengyan LiPeter I Lelkes
Sep 1, 2005·Journal of Biomaterials Science. Polymer Edition·Michiyo MiyoshiShigehiko Suzuki
Nov 4, 2005·Journal of Controlled Release : Official Journal of the Controlled Release Society·Simon YoungAntonios G Mikos
Mar 25, 2006·Biomaterials·Yuan JiMiriam H Rafailovich
Apr 1, 2006·Journal of Nanoscience and Nanotechnology·Patcharaporn WutticharoenmongkolPitt Supaphol
Jun 28, 2006·Journal of Microencapsulation·Sha HuangYan Jin
Nov 11, 2006·Journal of Biomaterials Science. Polymer Edition·Chidchanok MeechaisueJoachim Kohn
May 7, 2008·Biomedical Materials·Susan LiaoSeeram Ramakrishna


Apr 25, 2014·International Journal of Molecular Sciences·Lim Jeong, Won Ho Park
Jun 4, 2010·Cutaneous and Ocular Toxicology·Wen ZhongHoward I Maibach
Jul 20, 2010·International Journal of Biological Macromolecules·Juthamas RatanavarapornSiriporn Damrongsakkul
Sep 1, 2015·International Journal of Biological Macromolecules·Jorge PadrãoVitor Sencadas
Oct 20, 2015·Materials Science & Engineering. C, Materials for Biological Applications·Seza Özge GönenSadriye Küçükbayrak
May 26, 2012·Phytotherapy Research : PTR·Nunthawan NowwarotePrasit Pavasant
Feb 26, 2015·Journal of Tissue Engineering and Regenerative Medicine·Chun-Hsu YaoChiung-Hua Huang
Nov 6, 2015·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Wing P ChanMeng-Yi Bai
Oct 15, 2014·Asian Pacific Journal of Tropical Medicine·Richard Simo TagneAhsana Dar Farooq
Jan 4, 2021·Journal of Pharmaceutical Sciences·Wiphada RongthongWithawat Mingvanish
May 6, 2021·Macromolecular Bioscience·Matin RostamitabarSamaneh Ghazanfari

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