Electrospun Poly(ε-caprolactone)/Polyhedral Oligomeric Silsesquioxane-Based Copolymer Blends: Evolution of Fiber Internal Structures

Macromolecular Bioscience
Adam J P BauerBingbing Li

Abstract

This study reports the structural transition of electrospun poly(ε-caprolactone) (PCL)/poly[(propylmethacryl-heptaisobutyl-polyhedral oligomeric silsesquioxane)-co-(methyl meth-acrylate)] (POSS-MMA) blends, from PCL-rich fibers, to bicontinuous PCL core/POSS-MMA shell fibers, to POSS-MMA-rich fibers with a discontinuous PCL inner phase. A ternary phase diagram depicting the electrospinnability of PCL/POSS-MMA solutions is constructed by evaluating the morphological features of fibers electrospun from solutions with various concentrations and PCL/POSS-MMA blend ratios. X-ray diffraction, Raman spectroscopy, and differential scanning calorimetry are further used to characterize the electrospun PCL/POSS-MMA hybrid fibers. These physicochemical characterization results are thoroughly discussed to understand the internal structures of the hybrid fibers, which are directly correlated to the phase separation behavior of the electrospun solutions. The current study provides further insight into the complex phase behavior of POSS-copolymer-based systems, which hold great potential for a broad spectrum of biomedical applications.

References

May 17, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·Bingbing LiAlan R Esker
May 21, 2011·Macromolecular Rapid Communications·Hossein GhanbariAlexander M Seifalian
Sep 29, 2011·Small·Georg GeisbergerGreta R Patzke
Mar 15, 2012·Macromolecular Rapid Communications·Binbin JiangYongfeng Zhou
May 11, 2013·Journal of Materials Science. Materials in Medicine·Kyu-Oh KimIck-Soo Kim
Jun 12, 2013·Macromolecular Rapid Communications·Suntharavathanan Mahalingam, Mohan Edirisinghe
Sep 25, 2015·Molecular Pharmaceutics·Bahijja Tolulope Raimi-AbrahamDuncan Q M Craig

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