PMID: 15244629Jul 13, 2004Paper

Electrostatic contribution to twist rigidity of DNA

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
F Mohammad-Rafiee, Ramin Golestanian

Abstract

The electrostatic contribution to the twist rigidity of DNA is studied, and it is shown that the Coulomb self-energy of the double-helical sugar-phosphate backbone makes a considerable contribution-the electrostatic twist rigidity of DNA is found to be C(elec) approximately 5 nm, which makes up about 7% of its total twist rigidity ( C(DNA) approximately 75 nm). The electrostatic twist rigidity is found, however, to depend only weakly on the salt concentration, because of a competition between two different screening mechanisms: (1) Debye screening by the salt ions in the bulk, and (2) structural screening by the periodic charge distribution along the backbone of the helical polyelectrolyte. It is found that, depending on the parameters, the electrostatic contribution to the twist rigidity could stabilize or destabilize the structure of a helical polyelectrolyte.

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Citations

Feb 7, 2013·Journal of Biomolecular Structure & Dynamics·Davood Norouzi, Farshid Mohammad-Rafiee
Sep 7, 2018·Organic & Biomolecular Chemistry·Chandan PalTushar Kanti Chakraborty
Oct 22, 2010·European Biophysics Journal : EBJ·A G Cherstvy
Jul 23, 2008·Physical Review Letters·T B LiverpoolC A Laughton
Jul 9, 2016·Physical Review Letters·Onno D BroekmansGijs J L Wuite
Jan 5, 2019·Physical Review Letters·C I Trombley, M L Ekiel-Jeżewska
Apr 9, 2018·The Journal of Chemical Physics·Amir Rezaie-Dereshgi, Farshid Mohammad-Rafiee
Oct 14, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Sahin Buyukdagli, T Ala-Nissila
Oct 19, 2007·The Journal of Physical Chemistry. B·A G Cherstvy

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