Elevated alpha fetoprotein, no hepatocellular carcinoma

Journal of Clinical and Experimental Hepatology
Mallikarjun PatilChannagiri K Adarsh

Abstract

Alpha fetoprotein is a fetal specific glycoprotein which falls rapidly after birth. High level of alpha fetoprotein is suspicious of hepatocellular carcinoma but may be elevated in chronic viral hepatitis. A 35-year-old presented to us with jaundice for 7 days. He had chronic hepatitis B infection for last 12 months and was taking medicines irregularly for same. He had high alpha fetoprotein levels (740.9 ng/ml) without evidence of hepatocellular carcinoma which reduced with antiviral therapy. Such elevation can be explained due to hepatic inflammation and viral replication.

Citations

Sep 8, 2017·Artificial Cells, Nanomedicine, and Biotechnology·Abhishek K SahBina Gidwani
Nov 8, 2020·The International Journal of Biological Markers·Jamil A Al-Mughales, Mahmood Shaheen Alahwal
Nov 21, 2020·Molecular and Cellular Biochemistry·Saurabh K ChhonkerRaj Kumar Koiri
Aug 11, 2021·Viruses·Yashasavi SacharStephen E Congly

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