Abstract
Meigs' syndrome is the association of ovarian fibroma, pleural effusion, and ascites. Meigs' syndrome with marked elevation of CA125 is an unusual clinical condition reported in 27 cases in the literature. The patient was a 46-year-old woman with right pleural effusion, ascites, ovarian tumor, and CA125 level of 1808 U/mL. Tomography revealed ascites and bilobate pelvic tumor of approximately 25 cm. The diagnosis of advanced epithelial ovarian cancer was considered, and the patient was treated with chemotherapy. Three chemotherapy schemes were applied due to the total lack of response in tumor volume; however, CA125 decreased to 90 U/mL. Thus, surgery was performed with resection of 25 cm of the left ovarian tumor, with intact capsule and without implants; the result of histopathologic analysis was fibroma. Postoperative CA125 was 11 U/mL. Patients with elevated CA125 and ascites cytology positive for malignancy must be cautiously treated due to the possibility of false positives, even if the probability is low. Therefore, minimally invasive surgery for biopsy collection must be considered. Although the association between ovarian tumor, pleural effusion, ascites, and marked elevation of CA125 is highly indicative of epithelial...Continue Reading
References
Jul 1, 1992·Gynecologic Oncology·L L WilliamsH W Jones
Jan 1, 1991·Gynecologic Oncology·R E BullerM L Berman
Sep 1, 1990·Obstetrics and Gynecology·J L WalkerS Y Liao
Aug 1, 1988·American Journal of Obstetrics and Gynecology·G D MalkasianR E Ritts
Jan 1, 1983·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·S E KabawatR B Colvin
Oct 1, 1993·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Y H TuranF Ortaç
Jun 1, 1994·Journal of Surgical Oncology·P K Buamah, A W Skillen
Dec 1, 1995·Gynecologic Oncology·D TimmermanI Vergote
Sep 1, 1996·Gynecologic Oncology·A G ZeimetO Dapunt
Apr 7, 1999·European Journal of Obstetrics, Gynecology, and Reproductive Biology·A AbadJ Llixiona
Sep 21, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·S Lurie
Oct 12, 2000·The British Journal of Radiology·C Y ChanL Liauw
Nov 13, 2001·Obstetrics and Gynecology·B M ButtinT J Herzog
Apr 2, 2002·Gynecologic Oncology·Omer TopalakOktay Erten
Jul 3, 2003·Oncology·Alper SevincSuleyman Buyukberber
Dec 11, 2003·São Paulo Medical Journal = Revista Paulista De Medicina·Sabas Carlos VieiraJerúsia Oliveira Ibiapina de Santana
Jul 2, 2004·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·H Martínez-SaídC M López-Graniel
Citations
Sep 23, 2008·Archives of Gynecology and Obstetrics·Mabel Po MuiHextan Y S Ngan
Jan 24, 2009·World Journal of Surgical Oncology·Sophocles LanitisDimitri J Hadjiminas
Sep 10, 2011·JSLS : Journal of the Society of Laparoendoscopic Surgeons·Chang Eop SonJong Woon Bae
Aug 29, 2012·Case Reports in Obstetrics and Gynecology·Patrick RobertsLilian T Gien
Jun 26, 2014·BMC Surgery·Antonio MacciòAnna Maria Paoletti
May 23, 2014·Journal of Cancer Research and Clinical Oncology·Mingchen BaShuzhong Cui
Jun 29, 2013·Metabolism: Clinical and Experimental·Athanasios D AnastasilakisStergios Papachatzopoulos
Jul 28, 2011·Taiwanese Journal of Obstetrics & Gynecology·Jia-Hung LiouJui-Chang Hsu
Apr 29, 2014·Taiwanese Journal of Obstetrics & Gynecology·Wing-Yuk ChanPi-Hua Chen
Oct 31, 2008·Journal of Minimally Invasive Gynecology·Anastasia UssiaPhilippe R Koninckx
Aug 29, 2013·Case Reports in Anesthesiology·Manila Singh, Saket Singh
May 14, 2009·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Fatma Bahar CebesoyYelda Ibar
Jan 30, 2020·Kardiologiia·E I TarlovskayaK V Mazalov
Dec 2, 2017·Ultrasound Quarterly·Thelina AmaratungaAshraf Goubran
Aug 26, 2018·Medicine·Yuanming ShenXiaoyun Wan