PMID: 9442808Jan 27, 1998Paper

Elevated lipoprotein lipids and gestational hormones in women with diet-treated gestational diabetes mellitus compared to healthy pregnant controls

Journal of Diabetes and Its Complications
S C CouchC J Lammi-Keefe

Abstract

The objective of this study was to describe plasma and lipoprotein perturbations in gestational diabetes mellitus (GDM) compared to controls, and determine if alterations in lipids are related to gestational hormones and/or glucose control. Maternal HbA1c, free fatty acids (FFA), beta-estradiol, progesterone, prolactin, and plasma, very-low-density lipoprotein (VLDL), low-density lipoprotein (LDL), high-density lipoprotein (HDL), HDL2 and HDL3 triglyceride (TG), cholesterol, and dietary intake were determined for women with diet-treated GDM and controls in a longitudinal design. Subjects (N = 25/group) were matched for age, race, and body-mass index (BMI). Women with GDM had significantly higher HbA1c than controls, although both groups were within the normal range (4%-6%). However, body weight gain was less for women with GDM. There was a trend for higher plasma FFAs at 37-38 weeks in GDM versus controls. Plasma and lipoprotein TG among the groups increased over the third trimester, and mean concentrations were greater for women with GDM. In GDM versus controls, VLDL and HDL3 TGs were higher at all times, HDL and HDL2 TGs at 33-34 and 37-38 weeks, and LDL TGs at 37-38 weeks. In VLDL, core lipids (TG + cholesterol) increased ov...Continue Reading

References

Dec 1, 1979·British Journal of Obstetrics and Gynaecology·N G PipeT M Coltart
Apr 1, 1975·Metabolism: Clinical and Experimental·C J GlueckD Scheel
Apr 1, 1975·European Journal of Clinical Investigation·J A Elliott
Mar 1, 1978·Japanese Heart Journal·Y Handa
Aug 1, 1977·American Journal of Obstetrics and Gynecology·D S LinW E Connor
Dec 1, 1991·Journal of the American College of Nutrition·R H KnoppB Bonet
Apr 1, 1991·European Journal of Clinical Chemistry and Clinical Biochemistry : Journal of the Forum of European Clinical Chemistry Societies·A H Maas
Feb 1, 1988·The Journal of Clinical Endocrinology and Metabolism·R SorvaM R Taskinen
Jan 1, 1993·Diabetes Care·R M CowettP L Ogburn
Dec 1, 1996·Diabetes Care·C H Meyers-Seifer, B R Vohr

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Citations

Mar 29, 2008·Metabolic Syndrome and Related Disorders·Kristine Y Lain, Patrick M Catalano
May 5, 2012·PloS One·Gregory J AngerMicheline Piquette-Miller
Jun 23, 2010·Obstetrics and Gynecology·Anjel VahratianDawn P Misra
Nov 28, 2015·BMC Pregnancy and Childbirth·Abdulrahman Al-AjlanNasser M Al-Daghri
Dec 3, 2008·Diabetic Medicine : a Journal of the British Diabetic Association·M RizzoM Arslan
Jun 11, 2011·Diabetic Medicine : a Journal of the British Diabetic Association·U M Schaefer-GrafE Herrera
Sep 29, 2005·Diabetes Research and Clinical Practice·Daniel A EnquobahrieDavid A Luthy
Jan 23, 2015·BJOG : an International Journal of Obstetrics and Gynaecology·K K RyckmanA F Saftlas
May 15, 2004·The Science of the Total Environment·Gautam SamantaDipankar Chakraborti
Aug 14, 2010·Ecotoxicology and Environmental Safety·Elijah Oyoo-OkothElijah S Omutange
Sep 30, 2008·Arquivos brasileiros de endocrinologia e metabologia·Eliana M Da Ros WendlandMaria Inês Schmidt
Mar 30, 2016·The Journal of Clinical Endocrinology and Metabolism·Ravi RetnakaranBernard Zinman
Mar 30, 2010·The Journal of Pharmacology and Experimental Therapeutics·Gregory J Anger, Micheline Piquette-Miller
Dec 23, 2004·Journal of Hypertension·Anne BardenLawrence J Beilin
May 26, 2018·Human Fertility : Journal of the British Fertility Society·Mauro CozzolinoMaria Coccia Elisabetta
Feb 20, 2021·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Amy M ValentKent L Thornburg
Mar 9, 2021·Frontiers in Endocrinology·Yunting ZhouJianhua Ma
Jan 23, 2020·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·Manoharan BalachandiranRajaa Muthu Packirisamy

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