Elevated mercury exposure and neurochemical alterations in little brown bats (Myotis lucifugus) from a site with historical mercury contamination.

Ecotoxicology
Dong-Ha NamNiladri Basu

Abstract

Despite evidence of persistent methylmercury (MeHg) contamination in the South River (Virginia, USA) ecosystem, there is little information concerning MeHg-associated neurological impacts in resident wildlife. Here we determined mercury (Hg) concentrations in tissues of insectivorous little brown bats (Myotis lucifugus) collected from a reference site and a MeHg-contaminated site in the South River ecosystem. We also explored whether neurochemical biomarkers (monoamine oxidase, MAO; acetylcholinesterase, ChE; muscarinic acetylcholine receptor, mAChR; N-methyl-D-aspartate receptor, NMDAR) previously shown to be altered by MeHg in other wildlife were associated with brain Hg levels in these bats. Concentrations of Hg (total and MeHg) in tissues were significantly higher (10-40 fold difference) in South River bats when compared to reference sites. Mean tissue mercury levels (71.9 ppm dw in liver, 7.14 ppm dw in brain, 132 ppm fw in fur) in the South River bats exceed (sub)-clinical thresholds in mammals. When compared to the South River bats, animals from the reference site showed a greater ability to demethylate MeHg in brain (33.1% of total Hg was MeHg vs. 65.5%) and liver (8.9% of total Hg was MeHg vs. 50.8%) thus suggesting di...Continue Reading

References

Aug 1, 1977·Environmental Research·G V BurtonD Graff
Nov 1, 1978·Bulletin of Environmental Contamination and Toxicology·T MiuraI Nakamura
Aug 1, 1975·Bulletin of Environmental Contamination and Toxicology·P M Cumbie
Jan 1, 1990·Neuroscience and Biobehavioral Reviews·M Aschner, J L Aschner
Oct 1, 1990·Journal of Neurology, Neurosurgery, and Psychiatry·U BonuccelliA Muratorio
Jul 1, 1986·Journal of Wildlife Diseases·M J PybusD K Onderka
Sep 1, 1981·Canadian Journal of Biochemistry·G TomlinsonI McLennan
May 1, 1997·Bulletin of Environmental Contamination and Toxicology·R T StevensJ M Sleeman
Feb 11, 1998·Physiological Reviews·C MissaleM G Caron
Jul 8, 1998·Neuroscience Letters·S Kumar
Oct 19, 2000·Neuropathology : Official Journal of the Japanese Society of Neuropathology·K Eto
May 16, 2001·Bulletin of Environmental Contamination and Toxicology·M B HickeyC Soulliere
Jul 27, 2001·Brain Research Bulletin·A F CastoldiL Manzo
Jun 6, 2003·Progress in Neuro-psychopharmacology & Biological Psychiatry·Marta WeinstockMoussa Youdim
Jun 18, 2003·Critical Reviews in Toxicology·Edward J Calabrese, Linda A Baldwin
Jan 28, 2004·Annual Review of Pharmacology and Toxicology·Jürgen Wess
Jun 15, 2005·Environmental Science & Technology·Niladri BasuHing Man Chan
Feb 1, 2006·Toxicological Sciences : an Official Journal of the Society of Toxicology·Niladri BasuHing Man Chan
May 24, 2006·Environmental Research·Niladri BasuHing Man Chan
Sep 16, 2006·Critical Reviews in Toxicology·Thomas W Clarkson, Laszlo Magos
Dec 13, 2006·The Science of the Total Environment·April KinghornHing Man Chan
Apr 6, 2007·Ambio·Donna MerglerUNKNOWN Panel on Health Risks and Toxicological Effects of Methylmercury
Aug 8, 2007·Journal of the Neurological Sciences·Shigeo EkinoToshinori Kitamura
Apr 19, 2008·Science·Daniel A CristolAriel E White
Aug 23, 2008·Environmental Toxicology and Chemistry·Niladri BasuRune Dietz
Sep 8, 2009·Environmental Science & Technology·Haruka WadaWilliam A Hopkins
Jul 14, 2010·Environmental Monitoring and Assessment·Dong-Ha NamNiladri Basu
Aug 7, 2010·Journal of Wildlife Diseases·Jonathan M SleemanMichael K Keel
Sep 8, 2010·Environmental Toxicology and Chemistry·Christine M BergeronWilliam A Hopkins
Sep 8, 2010·Environmental Toxicology and Chemistry·Christine M BergeronWilliam A Hopkins
Jan 15, 2011·Chemistry Central Journal·Dong-Ha Nam, Niladri Basu

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Citations

Nov 26, 2013·Ecotoxicology·David E YatesNelson J O'Driscoll
May 21, 2014·Ecotoxicology·Khairunnisa SyaripuddinJohn-James Wilson
Jan 18, 2016·Chemosphere·Béatrice V HernoutAlistair B A Boxall
Sep 5, 2015·Environmental Pollution·Megan E LittleLinda M Campbell
Sep 27, 2014·Archives of Environmental & Occupational Health·Hamid ShirkhanlooHamid Hassani
Oct 19, 2016·Ecological Applications : a Publication of the Ecological Society of America·Ramsa Chaves-UlloaCelia Y Chen
Dec 29, 2016·Environmental Science and Pollution Research International·Fulgencio LisónAntonio J García-Fernández
May 9, 2016·Environmental Pollution·Béatrice V HernoutAlistair B A Boxall
Aug 10, 2017·Environmental Toxicology and Chemistry·Jennifer M KorstianAmanda M Hale
Nov 13, 2017·Bulletin of Environmental Contamination and Toxicology·Staffan Åkerblom, Johnny de Jong
May 10, 2017·Royal Society Open Science·Daniel J BeckerDaniel G Streicker
Jul 22, 2018·Archives of Environmental Contamination and Toxicology·Laura M HeikerClaire V Ramos
Jun 20, 2020·Environmental Science and Pollution Research International·Isela Hernández-PlataPatricia Mussali-Galante
Nov 5, 2017·Ecotoxicology·Mónica Moreno-BrushHarald Biester
Jun 23, 2018·The Science of the Total Environment·Nico W van den BrinkMaarten J J E Loonen
Apr 3, 2021·Archives of Environmental Contamination and Toxicology·Abby M WebsterN Roxanna Razavi
Oct 19, 2017·Environmental Pollution·Daniel J BeckerM Brock Fenton
Apr 30, 2021·The Journal of Applied Ecology·Daniel J BeckerMatthew M Chumchal

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