Elevated neutrophil-to-lymphocyte ratio in the diagnosis of Hashimoto's thyroiditis

Revista da Associação Médica Brasileira
G AktasH Savli

Abstract

Hashimoto's thyroiditis (HT) is an autoimmune inflammatory disorder. The purpose of this study was to determine the neutrophil-to-lymphocyte ratio (NLR), a novel marker of inflammation, in patients with HT and to compare these values with those from healthy subjects. A total of 154 participants were included in the study, 90 HT patients and 64 healthy volunteers. Retrospectively, demographic and laboratory data of the subjects were obtained from our institution's database. Patients with active infection, diabetes mellitus, malignancy, other chronic inflammatory diseases, hematologic disorders and patients on aspirin or steroid treatment were excluded from the study. Values for complete blood count (CBC) and serum laboratory parameters of HT patients were the baseline values obtained at the time of HT diagnosis. Control subjects consisted of healthy volunteers who visited our institution for a routine check-up. Age, gender and CBC parameters were not different between the HT group and the control group; however, the NLR of HT group (2.1 [1.3-5.8]) was significantly higher than the control group (1.9 [0.6-3.3]), p=0.04. Increased NLR may be useful as an indicator of the presence of HT, especially in complicated cases. NLR is inex...Continue Reading

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Citations

Jun 6, 2019·Revista da Associação Médica Brasileira·Ibrahim Karagoz, Hamit Yoldas
Oct 15, 2019·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Viktoria ChristoforakiCharalampos Siristatidis
Sep 19, 2019·Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry·Humaira B NoorMd A T Sagor
Aug 28, 2020·Revista da Associação Médica Brasileira·Asli Kurtar MansirogluYilmaz Gunes
Jun 30, 2019·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Satilmis BilginHaluk Savli
Jan 30, 2020·Revista da Associação Médica Brasileira·Ahmet UrkmezMetin Ishak Ozturk
Mar 9, 2021·Journal of Cosmetic Dermatology·Göktürk Dere, Mustafa Gündoğdu
Jun 10, 2021·Scandinavian Journal of Clinical and Laboratory Investigation·Eloísa UrrechagaUrko Aguirre
Jun 19, 2021·Romanian Journal of Internal Medicine = Revue Roumaine De Médecine Interne·Ozge KurtkulagiGulali Aktas
Aug 28, 2021·Journal of Cosmetic Dermatology·Julio ToralesMohammad Jafferany

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