Abstract
Hashimoto's thyroiditis (HT) is an autoimmune inflammatory disorder. The purpose of this study was to determine the neutrophil-to-lymphocyte ratio (NLR), a novel marker of inflammation, in patients with HT and to compare these values with those from healthy subjects. A total of 154 participants were included in the study, 90 HT patients and 64 healthy volunteers. Retrospectively, demographic and laboratory data of the subjects were obtained from our institution's database. Patients with active infection, diabetes mellitus, malignancy, other chronic inflammatory diseases, hematologic disorders and patients on aspirin or steroid treatment were excluded from the study. Values for complete blood count (CBC) and serum laboratory parameters of HT patients were the baseline values obtained at the time of HT diagnosis. Control subjects consisted of healthy volunteers who visited our institution for a routine check-up. Age, gender and CBC parameters were not different between the HT group and the control group; however, the NLR of HT group (2.1 [1.3-5.8]) was significantly higher than the control group (1.9 [0.6-3.3]), p=0.04. Increased NLR may be useful as an indicator of the presence of HT, especially in complicated cases. NLR is inex...Continue Reading
References
Feb 20, 1986·The New England Journal of Medicine·R Ross
Jan 24, 1981·British Medical Journal·W M TunbridgeE Young
Jan 1, 1995·Acta Oncologica·A SatomiM Sonoda
Jan 27, 1998·Circulation·S R OmmenR J Gibbons
Nov 18, 2000·European Journal of Endocrinology·T BjoroH Brochmann
Oct 16, 2001·The Journal of Clinical Endocrinology and Metabolism·M A García-LópezM Marazuela
Dec 13, 2003·Autoimmunity·R A Ajjan, A P Weetman
Sep 1, 2004·International Journal of Cardiology·Pablo AvanzasJosé Luis López-Sendón
Nov 3, 2004·Autoimmunity·Anthony P Weetman
Nov 26, 2005·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·G CsabaE Pállinger
May 23, 2006·Clinical Endocrinology·Guang-da XiangHui-Juan Xiang
Sep 14, 2006·The Journal of Clinical Endocrinology and Metabolism·Stefano TaddeiFabio Monzani
Mar 13, 2008·Journal of Surgical Oncology·Dhanwant GomezK Rajendra Prasad
Apr 17, 2008·Cancer Immunology, Immunotherapy : CII·Hanbyoul ChoKook Lee
May 24, 2008·Clinica Chimica Acta; International Journal of Clinical Chemistry·Angela PapaFranca Cocci
Jul 25, 2008·Nature·Alberto MantovaniFrances Balkwill
Sep 9, 2008·The American Journal of Cardiology·Umesh U TamhaneHitinder S Gurm
Feb 12, 2009·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·G Csaba, E Pállinger
Feb 12, 2010·Clinical Pharmacology and Therapeutics·M M MooreS J Clarke
Jul 21, 2010·The Journal of Urology·Yoshio OhnoMasaaki Tachibana
Sep 8, 2010·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Hideaki ShimadaMatsuo Nagata
Oct 20, 2010·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Steven C H KaoStephen J Clarke
Oct 5, 2011·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Basem AzabWarren D Widmann
Jan 28, 2012·International Archives of Medicine·Fauzia ImtiazSaadiyah Rao
Sep 22, 2012·Journal of Surgical Oncology·Chien-Liang LiuShih-Ping Cheng
Sep 25, 2012·Thyroid : Official Journal of the American Thyroid Association·Sara Salehi HammerstadKnut Dahl-Jørgensen
Oct 9, 2012·Atherosclerosis·Yaron ArbelShmuel Banai
Nov 26, 2013·Endocrine·Ju-Yeon KimEun Jung Jung
Oct 4, 2014·Journal of Clinical Laboratory Analysis·Jian LiChaohui Duan
Citations
Jun 6, 2019·Revista da Associação Médica Brasileira·Ibrahim Karagoz, Hamit Yoldas
Oct 15, 2019·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Viktoria ChristoforakiCharalampos Siristatidis
Sep 19, 2019·Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry·Humaira B NoorMd A T Sagor
Jul 14, 2020·Disease Markers·Li Yan, Zhi-De Hu
Aug 28, 2020·Revista da Associação Médica Brasileira·Asli Kurtar MansirogluYilmaz Gunes
Dec 23, 2019·Endocrine·Murat CalapkuluErman Cakal
Jun 18, 2020·Therapeutics and Clinical Risk Management·Shang QiaoShujun Guo
Oct 1, 2020·Journal of Clinical Medicine·Joanna SzydełkoBeata Matyjaszek-Matuszek
Jun 30, 2019·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Satilmis BilginHaluk Savli
Mar 3, 2020·Medicine·Fidel López-VerdugoGonzalo Torres-Villalobos
Jan 30, 2020·Revista da Associação Médica Brasileira·Ahmet UrkmezMetin Ishak Ozturk
Oct 18, 2020·World Journal of Surgery·Mehmet Buğra BozanAyşe Azak Bozan
Sep 8, 2020·Journal of Clinical Laboratory Analysis·Yi YangWanli Dong
Mar 9, 2021·Journal of Cosmetic Dermatology·Göktürk Dere, Mustafa Gündoğdu
Apr 4, 2021·Diagnostics·Ioana ȚaranuSorana D Bolboacă
May 6, 2021·Journal of Clinical Laboratory Analysis·Lingxiong ChaiQun Luo
Jun 12, 2021·Journal of Inflammation Research·Weijian EHaining Fan
Jun 10, 2021·Scandinavian Journal of Clinical and Laboratory Investigation·Eloísa UrrechagaUrko Aguirre
Jun 19, 2021·Romanian Journal of Internal Medicine = Revue Roumaine De Médecine Interne·Ozge KurtkulagiGulali Aktas
Aug 14, 2021·Health Science Reports·S M Yasir ArafatSheikh Shoib
Aug 15, 2021·Journal of Clinical Laboratory Analysis·Junjun WangYumin Wang
Aug 19, 2021·Clinics·Cínthia Minatel RiguettoDenise Engelbrecht Zantut-Wittmann
Aug 13, 2021·International Journal of Clinical Practice·Sumeyye Alparslan BekirZuhal Karakurt
Aug 28, 2021·Journal of Cosmetic Dermatology·Julio ToralesMohammad Jafferany
Sep 15, 2021·International Journal of Clinical Practice·Çağrı TuranDilek Tezcan
Nov 18, 2021·Journal of Clinical Laboratory Analysis·Yuru FanXin Zeng
Nov 24, 2021·Journal of Clinical Laboratory Analysis·Canyang ZhanLihua Chen
Nov 26, 2021·Journal of Clinical Laboratory Analysis·Kai DaiWenjun Xiong