PMID: 22358272Feb 24, 2012Paper

Elevated plasma D-dimer and hypersensitive C-reactive protein levels may indicate aortic disorders

Revista brasileira de cirurgia cardiovascular : órgão oficial da Sociedade Brasileira de Cirurgia Cardiovascular
Shi-Min YuanSong Gao

Abstract

D-dimer and C-reactive protein are of diagnostic and predictive values in patients have thrombotic tendency, such as vascular thrombosis, coronary artery disease and aortic dissection. However, the comparative study in these biomarkers between the patients with acute aortic dissection and coronary artery disease has not been sufficiently elucidated. Consecutive surgical patients for acute type A aortic dissection (20 patients), aortic aneurysm (nine patients) or coronary artery disease (20 patients) were selected into this study. Plasma from preoperative blood samples and supernatant of aortic homogenate of the surgical specimens were detected for D-dimer and hypersensitive C-reactive protein (hs-CRP). Plasma D-dimer and hs-CRP values in type A aortic dissection or aortic aneurysm were much higher than in coronary artery disease patients or the healthy control (for D-dimer, aortic dissection: coronary artery disease, 0.4344 ± 0.2958 µg/ml vs. 0.0512 ± 0.0845 µg/ml, P < 0.0001; aortic dissection: healthy control, 0.4344 ± 0.2958 µg/ml vs. 0.1250 ± 0.1295 µg/ml, P = 0.0005; aortic aneurysm: coronary artery disease, 0.4200 ± 0.4039 µg/ml vs. 0.0512 ± 0.0845 µg/ml, P = 0.0013; and aortic aneurysm: healthy control, 0.4200 ± 0.4039 µ...Continue Reading

References

Nov 26, 1987·The New England Journal of Medicine·J B KruskalR E Kirsch
May 20, 1999·Circulation·A J MossR B Case
Aug 31, 2000·American Heart Journal·A Bayes-GenisA B De Luna
Sep 5, 2001·Molecular Immunology·J E Volanakis
Jul 11, 2002·Intensive Care Medicine·Martin SchillingerMarcus Müllner
Jan 7, 2003·Annals of Emergency Medicine·Lorraine C MionCharles Emerman
May 13, 2003·Chest·Thomas WeberBernd Eber
Aug 21, 2003·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·H KinK Inada
Aug 18, 2004·Journal of the American College of Cardiology·Holger EggebrechtRaimund Erbel
Dec 3, 2004·Thrombosis Journal·Henri Mh SpronkHugo Ten Cate
Mar 26, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Koichi AkutsuTeruo Takano
Nov 8, 2005·International Heart Journal·Kimiaki KomukaiSeibu Mochizuki
Mar 25, 2006·Critical Care Medicine·Patrick OhlmannPierre Bareiss
Apr 21, 2006·Cardiovascular Research·Elaine Paffen, Moniek P M DeMaat
Jan 20, 2007·International Journal of Cardiology·Eftihia SbarouniDimitrios Th Kremastinos
Aug 3, 2007·Atherosclerosis·Radjesh J BisoendialErik S G Stroes
Feb 21, 2009·Revista brasileira de cirurgia cardiovascular : órgão oficial da Sociedade Brasileira de Cirurgia Cardiovascular·Edmo Atique GabrielEnio Buffolo
Apr 21, 2009·Journal of Cardiovascular Medicine·Domenico PaparellaLuigi de Luca Tupputi Schinosa
Dec 30, 2009·Hypertension·Kenichi SakakuraShin-ichi Momomura
Aug 19, 2010·Current Opinion in Cardiology·Toru SuzukiKim Eagle

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Citations

Dec 6, 2017·General Thoracic and Cardiovascular Surgery·Ayman A SaeyeldinJohn A Elefteriades
Jun 20, 2015·Indian Journal of Clinical Biochemistry : IJCB·Medha RajappaS Kumar
Oct 29, 2017·General Thoracic and Cardiovascular Surgery·Damian BalmforthMohamad Bashir
Jan 18, 2014·International Journal of Molecular Medicine·Ken-ichi MatsumotoTeiji Oda
Jan 8, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Alessandro ParolariDavide Pacini

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