Elevated risk for HIV-1 infection in adolescents and young adults in São Paulo, Brazil

PloS One
Katia Cristina BassichettoEsper Georges Kallas

Abstract

Recent studies have sought to describe HIV infection and transmission characteristics around the world. Identification of early HIV-1 infection is essential to proper surveillance and description of regional transmission trends. In this study we compare people recently infected (RI) with HIV-1, as defined by Serologic Testing Algorithm for Recent HIV Seroconversion (STARHS), to those with chronic infection. Subjects were identified from 2002-2004 at four testing sites in São Paulo. Of 485 HIV-1-positive subjects, 57 (12%) were defined as RI. Of the participants, 165 (34.0%) were aware of their serostatus at the time of HIV-1 testing. This proportion was statistically larger (p<0.001) among the individuals without recent infection (n = 158, 95.8%) compared to 7 individuals (4.2%) with recently acquired HIV-1 infection. In the univariate analysis, RI was more frequent in <25 and >59 years-old age strata (p<0.001). The majority of study participants were male (78.4%), 25 to 45 years-old (65.8%), white (63.2%), single (61.7%), with family income of four or more times the minimum wage (41.0%), but with an equally distributed educational level. Of those individuals infected with HIV-1, the predominant route of infection was sexual co...Continue Reading

References

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Citations

Sep 13, 2015·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Gorki GrinbergRicardo Sobhie Diaz
Nov 7, 2009·Revista Do Instituto De Medicina Tropical De São Paulo·Luiz Euribel Prestes-CarneiroJosé Alexandre Portelinha-Filho

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Methods Mentioned

BETA
circumcision
blood was drawn
pregnancy test
blood drawing

Software Mentioned

STARHS
Epi Info
Stata

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