Elevated temperature increases meiotic crossover frequency via the interfering (Type I) pathway in Arabidopsis thaliana

PLoS Genetics
Jennifer L ModliszewskiGregory P Copenhaver

Abstract

For most eukaryotes, sexual reproduction is a fundamental process that requires meiosis. In turn, meiosis typically depends on a reciprocal exchange of DNA between each pair of homologous chromosomes, known as a crossover (CO), to ensure proper chromosome segregation. The frequency and distribution of COs are regulated by intrinsic and extrinsic environmental factors, but much more is known about the molecular mechanisms governing the former compared to the latter. Here we show that elevated temperature induces meiotic hyper-recombination in Arabidopsis thaliana and we use genetic analysis with mutants in different recombination pathways to demonstrate that the extra COs are derived from the major Type I interference sensitive pathway. We also show that heat-induced COs are not the result of an increase in DNA double-strand breaks and that the hyper-recombinant phenotype is likely specific to thermal stress rather than a more generalized stress response. Taken together, these findings provide initial mechanistic insight into how environmental cues modulate plant meiotic recombination and may also offer practical applications.

References

Feb 21, 1998·Proceedings of the National Academy of Sciences of the United States of America·G P CopenhaverD Preuss
Sep 9, 1999·The Journal of Cell Biology·E P RogakouW M Bonner
Mar 30, 2000·Cytometry·G M van Kempen, L J van Vliet
Feb 7, 2001·The EMBO Journal·M GrelonG Pelletier
Jun 13, 2003·Nature·Igor KovalchukBarbara Hohn
Aug 13, 2003·The Journal of Biological Chemistry·Patrick SungMichael G Sehorn
Jul 22, 2006·Biochemical Society Transactions·F C H FranklinG H Jones
Jul 29, 2006·Cell·Emmanuelle MartiniScott Keeney
Aug 8, 2006·Nature·Jean MolinierBarbara Hohn
Sep 19, 2006·Plant Physiology·Kirk E FrancisGregory P Copenhaver
Mar 6, 2007·The Plant Cell·Franck G P LhuissierChrista Heyting
Mar 16, 2007·Proceedings of the National Academy of Sciences of the United States of America·Kirk E FrancisGregory P Copenhaver
Aug 19, 2007·PLoS Genetics·Luke E BerchowitzGregory P Copenhaver
Sep 6, 2007·Genes & Development·Eugenio Sanchez-MoranF Christopher H Franklin
Jun 27, 1913·Science·A H Sturtevant
Nov 9, 2007·PLoS Biology·Melissa S McMahillDouglas K Bishop
Jun 13, 2008·Nature Protocols·Thomas D Schmittgen, Kenneth J Livak
Jul 11, 2008·Nature·Eugenio ManceraLars M Steinmetz
Apr 22, 2009·PloS One·Ales PecinkaOrtrun Mittelsten Scheid
Oct 5, 2010·Current Genomics·Luke E Berchowitz, Gregory P Copenhaver
Mar 4, 2011·The New Phytologist·Kim OsmanF Chris H Franklin
May 17, 2012·The Plant Cell·Marie-Therese KurzbauerPeter Schlögelhofer
Jun 23, 2012·Science·Wayne CrismaniRaphaël Mercier
Jun 30, 2012·Nature Methods·Johannes SchindelinAlbert Cardona
Jul 31, 2012·PLoS Genetics·Liudmila ChelyshevaMathilde Grelon
Dec 11, 2014·Annual Review of Plant Biology·Raphaël MercierMathilde Grelon
Apr 1, 2015·Proceedings of the National Academy of Sciences of the United States of America·Mathilde Séguéla-ArnaudRaphael Mercier
Aug 11, 2015·The New Phytologist·Dylan PhillipsLuke Ramsay
Mar 5, 2017·Current Opinion in Plant Biology·Jennifer L Modliszewski, Gregory P Copenhaver
Nov 8, 2017·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jessica StapleyCarole M Smadja
Nov 8, 2017·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Christopher H MorganKirsten Bomblies
Jan 5, 2018·Journal of Experimental Botany·Christopher G OakleyDouglas W Schemske

❮ Previous
Next ❯

Citations

Jan 24, 2019·Genetics·Andrew Lloyd, Eric Jenczewski
Sep 5, 2019·Plant Biotechnology Journal·Ruud A de MaagdYuling Bai
Oct 7, 2019·Journal of Experimental Botany·Zhenyi ChangXiaoyan Tang
Sep 30, 2020·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Mikel ArrietaLuke Ramsay
Nov 30, 2018·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·A Blary, E Jenczewski
Jun 19, 2019·Molecular Biology and Evolution·Steven DreissigStefan Heckmann
Oct 17, 2018·Frontiers in Plant Science·Lorenz K FuchsDylan W Phillips
Mar 4, 2019·Chromosoma·Cori K Cahoon, Diana E Libuda
Apr 19, 2020·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Simon D BrownAlexander Lorenz
Mar 27, 2020·International Journal of Molecular Sciences·Wei RenQingchun Pan
Nov 28, 2018·Nature Plants·Delphine MieuletRaphael Mercier
Jun 9, 2021·Current Biology : CB·Petra BulankovaLieven De Veylder
May 6, 2021·The Plant Journal : for Cell and Molecular Biology·Yun-Jae AhnStefan Heckmann
Aug 14, 2021·Proceedings of the National Academy of Sciences of the United States of America·Longfei ZhuPiotr A Ziolkowski
Jul 27, 2021·Annual Review of Genetics·Ian R Henderson, Kirsten Bomblies

❮ Previous
Next ❯

Methods Mentioned

BETA
salt stress
PCR
salt treatment

Software Mentioned

Fiji
Image Tool
Adobe Photoshop
R
TetradAnalysis

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.