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Elevated thromboxane levels in the rat during endotoxic shock: protective effects of imidazole, 13-azaprostanoic acid, or essential fatty acid deficiency

The Journal of Clinical Investigation

Jan 1, 1980

James A CookPerry V Halushka

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Abstract

The potential deleterious role of the proaggregatory vasoconstrictor, thromboxane A(2), in endotoxic shock was investigated in rats. Plasma thromboxane A(2) was determined by radioimmunoassay of its stable metabolite thromboxane B(2). After intravenous administration of Salmonella enter...read more

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    • Citations90
  • Elevated thromboxane levels in the rat during endotoxic shock: protective effects of imidazole, 13-azaprostanoic acid, or essential fatty acid deficiency

    The Journal of Clinical Investigation

    Jan 1, 1980

    James A CookPerry V Halushka

    PMID: 7350199

    DOI: 10.1172/jci109655

    Abstract

    The potential deleterious role of the proaggregatory vasoconstrictor, thromboxane A(2), in endotoxic shock was investigated in rats. Plasma thromboxane A(2) was determined by radioimmunoassay of its stable metabolite thromboxane B(2). After intravenous administration of Salmonella enter...read more

    6

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    • Citations90
    • References9
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