PMID: 9649094Jul 2, 1998Paper

Elevated umbilical cord plasma erythropoietin levels in prolonged pregnancies

Obstetrics and Gynecology
A JazayeriW N Spellacy

Abstract

To determine if umbilical cord plasma erythropoietin levels are elevated in pregnancies that continue beyond their expected date for delivery. Erythropoietin was measured using an enzyme-linked immunosorbent assay in 124 appropriately grown newborns delivered from 37-43 weeks' gestation. Each woman had an uncomplicated labor and delivery course without evidence of fetal stress or meconium. The comparison was made between pregnancies ending at 37-40 weeks' gestation and those at 41-43 weeks' gestation. There was no difference between the two groups in cord blood gases or Apgar scores at 1 and 5 minutes. Cord plasma erythropoietin levels were significantly higher in pregnancies delivered after 41 completed weeks' gestation (41 or more weeks: 48.0+/-7.1 mIU/mL, n=45 versus 37-40 weeks: 26.1+/-4.2 mIU/mL, n=79, P < .001). When compared with pregnancies delivered between 37 and 40 weeks, erythropoietin levels were significantly elevated in pregnancies delivered at either 41, 42, or 43 weeks' gestation. In pregnancies reaching 41 weeks and beyond, cord plasma erythropoietin levels are significantly increased, indicating altered fetal oxygenation in some of these pregnancies. These results support the current practice of close fetal s...Continue Reading

References

Apr 1, 1995·American Journal of Obstetrics and Gynecology·S D RicheyL C Gilstrap
Feb 1, 1993·American Journal of Obstetrics and Gynecology·R J SnijdersK H Nicolaides
Oct 1, 1995·Acta Paediatrica·F de ZegherH Devlieger

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Citations

Oct 25, 2000·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·G GuptaN K Ganguly
Jan 22, 2000·Journal of Perinatal Medicine·R AxtW Schmidt
Oct 23, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Zeljko MikovicNatasa Simin
Aug 2, 2000·American Journal of Obstetrics and Gynecology·A JazayeriW N Spellacy
Aug 5, 2004·Obstetrics and Gynecology·Tamar PerriMichael Y Divon
Apr 23, 2002·Acta Obstetricia Et Gynecologica Scandinavica·Kari A TeramoJohn A Widness
Jan 10, 2021·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Mikko TarvonenKari Teramo
Dec 18, 2019·Neonatology·Mikko TarvonenKari Teramo

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