Elicitation of natural killer cells in beige mice by infection with vesicular stomatitis virus.

Infection and Immunity
K P McKinnonM J Ruebush

Abstract

Vesicular stomatitis virus (VSV) infection of beige (bg/bg) mice induced levels of natural killer cytolytic activity comparable to that of uninfected normal bg/+ controls, but considerably less than natural killer activity in VSV-infected bg/+ mice. In contrast, VSV-infected bg/bg and bg/+ mice had essentially equivalent amounts of anti-VSV cytotoxic T-lymphocyte and antibody activity. VSV infection induced comparable levels of interferon in both bg/bg and bg/+ mice. Therefore, the decreased natural killer activity in bg/bg mice could not be attributed to an inability to produce interferon.

References

Feb 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·A H HaleH N Eisen
Jan 1, 1974·Advances in Immunology·J C Cerottini, K T Brunner
Oct 1, 1973·European Journal of Immunology·M H JuliusL A Herzenberg
Jan 1, 1980·Scandinavian Journal of Immunology·R M Welsh, R W Kiessling
Apr 17, 1980·Nature·J E TalmadgeJ R Starkey

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Citations

Apr 15, 1985·International Journal of Cancer. Journal International Du Cancer·T HaliotisJ C Roder
Jan 21, 1982·Nature·R K SaxenaW H Adler
Jan 1, 1982·Springer Seminars in Immunopathology·B Rager-Zisman, B R Bloom
Feb 23, 2012·International Immunology·Connie JackamanDelia J Nelson

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