Elimination of false-positive results in a luminex assay for pneumococcal antibodies.

Clinical and Vaccine Immunology : CVI
Jerry W PickeringHarry R Hill

Abstract

In our 14-valent Luminex assay for pneumococcal antibodies, we identified two groups of sera that caused false-positive results. The first group bound nonspecifically to the Luminex microspheres. The second group reacted specifically with bovine serum albumin (BSA). We describe here methods that eliminated the false-positive reactivity of both groups.

References

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Apr 10, 2002·American Journal of Clinical Pathology·Jerry W PickeringHarry R Hill
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Mar 12, 2004·Clinical and Diagnostic Laboratory Immunology·Thomas B MartinsHarry R Hill
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Citations

May 24, 2013·Clinical and Vaccine Immunology : CVI·Harry R Hill, Jerry W Pickering
May 3, 2013·PloS One·Ratthaphol CharlermrojChristopher T Elliott
Jun 4, 2010·Expert Review of Vaccines·Peter D BurbeloMichael J Iadarola
May 12, 2016·Journal of Virological Methods·Fimme J van der WalWillie L A Loeffen
Oct 25, 2013·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Jane Christopher-HenningsJoan K Lunney
Apr 27, 2018·Journal of Clinical Microbiology·Jeffrey C ChandlerSarah N Bevins
Dec 19, 2014·Clinical and Vaccine Immunology : CVI·Thomas M Daly, Harry R Hill
Aug 12, 2018·Journal of Immunological Methods·David C LaFon, Moon H Nahm

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