Ellipsoid Zone Change According to Glaucoma Stage Advancement

American Journal of Ophthalmology
Ahnul HaKi Ho Park

Abstract

To compare retinal photoreceptor ellipsoid zone (EZ) intensity between normal eyes and those with different stages of glaucoma. Retrospective cross-sectional study. The study included 37 normal, 38 preperimetric glaucoma, 39 mild-to-moderate glaucoma (visual field [VF] mean deviation [MD]: -7.7 ± 2.0 dB), and 36 severe glaucoma eyes (VF MD: -17.8 ± 3.2 dB). The subjects underwent high-resolution horizontal and vertical line scans through the fovea by spectral-domain optical coherence tomography (SD-OCT). Image processing software was employed to quantify the intensity of the first and second hyperreflective bands corresponding with the external limiting membrane (ELM) and EZ. In order to account for the brightness variation among scans, the relative EZ intensity as the ratio of the second to first reflective band (EZ/ELM) was determined. The relative EZ intensity in severe glaucoma eyes was significantly lower than in mild-to-moderate glaucoma eyes (2.46 ± 0.38 vs 3.15 ± 0.43, P < .001); also, it was lower in mild-to-moderate than in preperimetric glaucoma eyes (3.15 ± 0.43 vs 3.86 ± 0.44, P < .001). However, the comparison between preperimetric glaucoma and normal eyes showed no significant difference (3.86 ± 0.44 vs 4.06 ± 0....Continue Reading

Citations

Apr 18, 2020·Investigative Ophthalmology & Visual Science·Ahnul HaKi Ho Park
Apr 18, 2019·PloS One·Junko OuchiToru Nakazawa
May 5, 2021·American Journal of Ophthalmology·Parmita MehtaUNKNOWN UK Biobank Eye and Vision Consortium

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Related Papers

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Tomoya MurakamiTetsuro Oshika
Investigative Ophthalmology & Visual Science
Sung Chul ParkR Ritch
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
Panagiotis TheodossiadisGeorge Theodossiadis
© 2022 Meta ULC. All rights reserved