Elschnig's spots in the acute and remission stages in preeclampsia: spectral-domain optical coherence tomographic features

European Journal of Ophthalmology
Ala'a AlTalbishiRadgonde Amer

Abstract

Preeclampsia is a multisystem disorder defined as new onset of hypertension and proteinuria during the second half of pregnancy. Serous retinal detachment (SRD) is a known complication of preeclampsia caused by choroidal ischemia and subsequent disruption of blood-retinal barrier. Poor perfusion of the choriocapillaris causes Elschnig's spots. We aim to describe distinctive optical coherence tomography (OCT) features of a cluster of Elschnig's spots in a patient with severe preeclampsia during the acute and remission stages. We also present a summary of OCT features of preeclampsia patients with SRD. Descriptive case report. V-shaped adhesions were observed at the location of each of the Elschnig's spots, the center of which showed disruption of the outer retinal bands (external limiting membrane, inner segment/outer segment junction layer), and the V-shaped outer parts remained tethered to retinal pigment epithelium (RPE)-Bruch's complex by hyperreflective exudate on the surface of RPE. These features parallel the histopathologic features described earlier. In an experimental model, Elschnig's spots showed a gradient of RPE damage from the center to the periphery, where RPE was necrotic in the center and edematous in the perip...Continue Reading

References

May 7, 2002·American Journal of Ophthalmology·Panagiotis G TheodossiadisGeorge P Theodossiadis
Apr 19, 2006·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Gábor Márk SomfaiJános Rigó
Sep 1, 2007·Seminars in Ophthalmology·Sofia AndroudiPeriklis D Brazitikos
Oct 23, 2009·Acta Ophthalmologica·Andreas Thorsrud, Emilia Kerty
Jan 30, 2013·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Marco R PastoreLuisa Pierro
Jul 23, 2013·Archives of Gynecology and Obstetrics·Lea QuerquesFrancesco Bandello
Aug 22, 2013·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Khawla Abu Samra
Sep 10, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Young-seok SongAkitoshi Yoshida

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Citations

Nov 28, 2018·International Ophthalmology·Camila Zanella BenficaDaniel Lavinsky
May 3, 2019·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Zhenzhen ZhangXiuhong Qin
Mar 30, 2021·Journal of Ophthalmology·Xinyi HeYuhua Tong
Aug 21, 2021·Klinische Monatsblätter für Augenheilkunde·Teresa Barth, Horst Helbig

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