PMID: 9422568Jan 9, 1998Paper

Elucidating the etiology of erectile dysfunction after definitive therapy for prostatic cancer

International Journal of Radiation Oncology, Biology, Physics
M J Zelefsky, J F Eid

Abstract

To determine the etiology of treatment-induced erectile dysfunction among patients who underwent surgery or radiotherapy for prostatic cancer. Ninety-eight patients were evaluated for erectile dysfunction after definitive therapy for prostate cancer with Duplex ultrasonography before and after intracorporal prostaglandin injection. Patients were classified as having arteriogenic, cavernosal, mixed (arteriogenic/cavernosal), or neurogenic impotence based upon the results of the Duplex studies. Among patients who underwent radical prostatectomy (RP), 31 (52%) had cavernosal dysfunction, 19 (32%) had arteriogenic dysfunction, 3 (5%) were classified as mixed, and 7 (12%) as neurogenic dysfunction. Among patients treated with radiotherapy (RT), 24 (63%) had arteriogenic dysfunction, 12 (32%) had cavernosal dysfunction, 1 (2.5%) were classified as mixed, and 1 (2.5%) as neurogenic dysfunction. A multivariate analysis identified prior RT as the only predictor of an arteriogenic etiology (p < 0.001) and prior RP as the only predictor of a cavernosal etiology (p < 0.04) for erectile dysfunction among these patients. In the RP and RT groups, the median erectile responses were 70 and 65%, respectively. Arterial peak flows < 25 cc/min pred...Continue Reading

References

Oct 1, 1991·International Journal of Radiation Oncology, Biology, Physics·L J PierceR L Goodman
Aug 1, 1990·The Urologic Clinics of North America·T F Lue
Dec 1, 1989·The Journal of Urology·R ShabsighJ K Dunn
Oct 1, 1989·The Australian and New Zealand Journal of Surgery·A K HemalN Malik
Jul 1, 1988·International Journal of Radiation Oncology, Biology, Physics·F L Banker
May 1, 1987·The Journal of Urology·T F Lue, E A Tanagho
Jun 1, 1985·International Journal of Radiation Oncology, Biology, Physics·B Mittal
May 1, 1993·The Journal of Urology·S E LernerG J Christ
Jul 1, 1963·British Journal of Plastic Surgery·J PENN

❮ Previous
Next ❯

Citations

Oct 3, 2001·International Journal of Cancer. Journal International Du Cancer·G S MerrickS Sutlief
Oct 13, 2011·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Freerk T BaumannWilhelm Bloch
Apr 25, 2006·Current Urology Reports·Stacy Loeb, Robert B Nadler
May 30, 2013·Current Urology Reports·Kamal Nagpal, Nelson Bennett
May 14, 2005·International Journal of Radiation Oncology, Biology, Physics·Gregory S MerrickZachariah A Allen
Sep 20, 2005·International Journal of Radiation Oncology, Biology, Physics·Patrick W McLaughlinJames Montie
Dec 20, 2003·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Gregory S Merrick, Wayne M Butler
Oct 31, 2000·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M al-AbanyA R Helgason
Dec 6, 2000·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·J Vale
Nov 10, 2000·International Journal of Radiation Oncology, Biology, Physics·G S MerrickJ G Donzella
Jun 8, 2001·International Journal of Radiation Oncology, Biology, Physics·G S MerrickM L Benson
Aug 3, 2001·International Journal of Radiation Oncology, Biology, Physics·L PottersM W Kattan
Feb 19, 2002·International Journal of Radiation Oncology, Biology, Physics·Luca IncrocciPeter C Levendag
Jul 4, 2002·International Journal of Radiation Oncology, Biology, Physics·Kent E WallnerBryan G Tollenaar
Aug 17, 2002·International Journal of Radiation Oncology, Biology, Physics·Michael D BastaschE Brian Butler
Sep 24, 2002·International Journal of Radiation Oncology, Biology, Physics·Subir NagUNKNOWN American Brachytherapy Society
Nov 7, 2002·International Journal of Radiation Oncology, Biology, Physics·Gregory S MerrickMark L Benson
Feb 28, 2003·International Journal of Radiation Oncology, Biology, Physics·Anil SethiJohn Mulhall
Feb 18, 2004·International Journal of Radiation Oncology, Biology, Physics·Mark K BuyyounouskiAlan Pollack
Dec 31, 2002·Urologic Oncology·Tony Y EngTerrence S Herman
Jul 10, 2012·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·M RouprêtF Desgrandchamps
Aug 24, 2000·American Journal of Clinical Oncology·R B WilderR D White
Aug 7, 2009·American Journal of Clinical Oncology·William M MendenhallNancy P Mendenhall
Apr 6, 2000·Psychosomatics·E J KunkelL G Gomella
Oct 12, 2012·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·A MagliS Fongione
Feb 10, 2016·Prostate Cancer and Prostatic Diseases·G GandagliaA Briganti
May 21, 2009·The Journal of Sexual Medicine·Gerard J van der WielenLuca Incrocci
Feb 13, 2009·The Journal of Sexual Medicine·Patrick E TelokenJohn P Mulhall
Jan 23, 2010·The Journal of Sexual Medicine·Richard SadovskyLuca Incrocci
Jun 18, 2011·The Journal of Sexual Medicine·Masaki KimuraBridget F Koontz
Dec 15, 2010·The Journal of Sexual Medicine·Bridget F KoontzFang-Fang Yin
Sep 22, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Claudio FiorinoGiuseppe Sanguineti
May 5, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Lucia PernaRiccardo Calandrino

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.